DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment aurB and Aurkc

DIOPT Version :9

Sequence 1:	NP_477336.1	Gene:	aurB / 34504	FlyBaseID:	FBgn0024227	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	XP_038959704.1	Gene:	Aurkc / 292554	RGDID:	1309573	Length:	329	Species:	Rattus norvegicus

Alignment Length:	255	Identity:	133/255 - (52%)
Similarity:	192/255 - (75%)	Gaps:	2/255 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 DFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHPHILRL 116
            |||:|..|||||||||||||.:.:|::||:||:||.|:.|..::.|:.||:||||.|:||:||||
  Rat    62 DFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIGKEGLEHQLRREVEIQSHLQHPNILRL 126

  Fly   117 LTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLNNVIHRDLKP 181
            ..:|:|:||:||.||.|..|||:|.|:  .|.:.::.|:|....::::||.|||.|.||||||||
  Rat   127 YNYFYDDSRVYLILEYAPRGELYKELQ--RNQKLNQQRTATIIEELSDALIYCHRNKVIHRDLKP 189

  Fly   182 ENILLTSTDDLKLADFGWSAHTPNNKRRTLCGTLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVV 246
            ||:||....::|:||||||.|||:.:|:|:|||||||||||::|.||:::||.||:|:||||.:|
  Rat   190 ENLLLGLKGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGKSYNETVDLWCIGVLCYELLV 254

  Fly   247 GCPPFESNSTESTYSKIRRMEISYPSHLSKGCKELIGGLLRKESKGRITLVDVMTHYWVK 306
            |.|||||:::..|..:|.:::..:||.:..|.::||..|||.....|::|..|:.|.||:
  Rat   255 GKPPFESSTSSETCRRICQVDFRFPSSMPAGAQDLISKLLRHHPSERLSLAQVLKHPWVR 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aurB	NP_477336.1	STKc_Aurora	52..306	CDD:270909	132/253 (52%)
Aurkc	XP_038959704.1	PKc_like	56..325	CDD:419665	133/255 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D318112at33208
OrthoFinder	1	1.000	-	-		FOG0000946
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100573
Panther	1	1.100	-	-	O	PTHR24350
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X555
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.820