Protein Alignment aurB and Aurka

DIOPT Version :9

• Sequence 1: NP_477336.1
• Gene: aurB / 34504
• FlyBaseID: FBgn0024227
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_035627.1
• Gene: Aurka / 20878
• MGIID: 894678
• Length: 417
• Species: Mus musculus
• Alignment Length: 309
• Identity: 143/309 - (46%)
• Similarity: 213/309 - (68%)
• Gaps: 10/309 - (3%)

  Fly     3 LSRAKHANRNHLPHLLAKVPEEHQEPIKNMCLKMMSHDAYGQPYDWSPRDFEMGAHLGRGKFGRV 67
            :||..:..:|..|.......|:.|..::.      :.|.  :...|:..||::|..||:||||.|
Mouse   104 VSRLNNPQKNEQPAASGNDSEKEQASLQK------TEDT--KKRQWTLEDFDIGRPLGKGKFGNV 160

  Fly    68 YLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHPHILRLLTWFHDESRIYLALEI 132
            ||||||.|.:::|:||:||.:|.|..|:.|:.||:||||.|:||:||||..:|||.:|:||.||.
Mouse   161 YLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY 225

  Fly   133 ASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLADF 197
            |..|.:::.|:..  .:|||.|:|.|..::||||:|||...|||||:||||:||.|..:||:|||
Mouse   226 APLGTVYRELQKL--SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADF 288

  Fly   198 GWSAHTPNNKRRTLCGTLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSK 262
            |||.|.|:::|.|:|||||||||||::|..:|:.||.|.||:|||||:||.||||:::.:.||.:
Mouse   289 GWSVHAPSSRRTTMCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRR 353

  Fly   263 IRRMEISYPSHLSKGCKELIGGLLRKESKGRITLVDVMTHYWVKAGMAE 311
            |.|:|.::|..:::|.::||..||:..:..|:||.:|:.|.|:||..::
Mouse   354 ISRVEFTFPDFVTEGARDLISRLLKHNASQRLTLAEVLEHPWIKANSSK 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurB	NP_477336.1	STKc_Aurora	52..306	CDD:270909	133/253 (53%)
Aurka	NP_035627.1	STKc_Aurora-A	140..396	CDD:271018	133/257 (52%)
		S_TKc	146..396	CDD:214567	131/251 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000946
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100573
Panther	1	1.100	-	-	O	PTHR24350
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X555
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810