Protein Alignment aurB and Prkacb

DIOPT Version :10

• Sequence 1: NP_477336.1
• Gene: aurB / 34504
• FlyBaseID: FBgn0024227
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_001157672.1
• Gene: Prkacb / 18749
• MGIID: 97594
• Length: 398
• Species: Mus musculus
• Alignment Length: 309
• Identity: 98/309 - (31%)
• Similarity: 150/309 - (48%)
• Gaps: 30/309 - (9%)

  Fly    23 EEHQEPIKNMCLKMMSHDAYGQ----------------------PYDWSPRDFEMGAHLGRGKFG 65
            :||:..:::..|:...|.|...                      |.:....|||....||.|.||
Mouse    39 QEHRAALEDDGLRASEHTASWDKSMKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFG 103

  Fly    66 RVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHPHILRLLTWFHDESRIYLAL 130
            ||.|.:.:.:....|||::.|:::.|.......|.|..|...::.|.::||...|.|.|.:|:.:
Mouse   104 RVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVM 168

  Fly   131 EIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLA 195
            |....||:|.|||..  .||.||.:..|..|:.....|.|..::|:|||||||:|:.....:::.
Mouse   169 EYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVT 231

  Fly   196 DFGWSAHTPNNKRRTLCGTLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTY 260
            |||: |.....:..|||||.:||.||::....|:.:||.|.||:|.||...|.|||.::.....|
Mouse   232 DFGF-AKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY 295

  Fly   261 SKIRRMEISYPSHLSKGCKELIGGLLRKESKGRI-----TLVDVMTHYW 304
            .||...::.:|||.|...|:|:..||:.:...|.     .:.|:.||.|
Mouse   296 EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKW 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurB	NP_477336.1	STKc_Aurora	52..306	CDD:270909	92/258 (36%)
Prkacb	NP_001157672.1	STKc_PKA	89..378	CDD:271111	92/259 (36%)