DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dnz1 and AKR1

DIOPT Version :9

Sequence 1:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_010550.1	Gene:	AKR1 / 851857	SGDID:	S000002672	Length:	764	Species:	Saccharomyces cerevisiae

Alignment Length:	142	Identity:	37/142 - (26%)
Similarity:	63/142 - (44%)	Gaps:	18/142 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VTYGAVLYADYVVIRW---IILTTMPGSLWMSFHVVLFNTVVFLLAMSHSKAVFSDPGTVPLPAN 76
            |.:|.:|   :|.|.|   ::..|.....:.:..:::....||.|   ..:.|..|||.:|   .
Yeast   391 VFFGTLL---WVTIVWFFKVMPRTFSDEQYTNILMLVILVSVFYL---FGQLVIMDPGCLP---E 446

  Fly    77 RLDFSDLHTTNKNNPPPGNGHSSEWTVCTRCETY--RPPRAHHCRICKRCIRRMDHHCPWINNCV 139
            ..|..::..|..|....|...:..:.:    ||:  :|.|:....:....:.|.||:||||.|.|
Yeast   447 ETDHENVRQTISNLLEIGKFDTKNFCI----ETWIRKPLRSKFSPLNNAVVARFDHYCPWIFNDV 507

  Fly   140 GERNQKYFLQFL 151
            |.:|.|.|:.|:
Yeast   508 GLKNHKAFIFFI 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	18/57 (32%)
AKR1	NP_010550.1	ANK repeat	75..101	CDD:293786
		ANKYR	78..270	CDD:223738
		ANK repeat	103..140	CDD:293786
		ANK repeat	142..173	CDD:293786
		ANK repeat	213..244	CDD:293786
		ANK repeat	246..271	CDD:293786
		COG5273	363..725	CDD:227598	37/142 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810