Protein Alignment Dnz1 and ZDHHC16

DIOPT Version :10

• Sequence 1: NP_477449.1
• Gene: Dnz1 / 34503
• FlyBaseID: FBgn0027453
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_115703.2
• Gene: ZDHHC16 / 84287
• HGNCID: 20714
• Length: 377
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 78/302 - (25%)
• Similarity: 125/302 - (41%)
• Gaps: 75/302 - (24%)

  Fly    10 IACLVVTYGAVLYADYVVIRWIILTT--MPGSLWMSFHVVLFNTVVFLLAMSHSKAVFSDPGTVP 72
            :..::|..|:::...|:.:..:||.|  :|...|   |....:..:.|:...:.:|:.:.||
Human    84 VVLVIVLTGSIVAIAYLCVLPLILRTYSVPRLCW---HFFYSHWNLILIVFHYYQAITTPPG--- 142

  Fly    73 LPANRLDFSDLHTTNKNNPPPGNGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMDHHCPWINN 137
                             .||.|....:..::|.:|...:|.|.|||.||.||:.:|||||||:||
Human   143 -----------------YPPQGRNDIATVSICKKCIYPKPARTHHCSICNRCVLKMDHHCPWLNN 190

  Fly   138 CVGERNQKYFLQFLIYVALLSLYSIALIVGSW---------VWPCEECSQNVIET---------- 183
            |||..|.:||..|..::.|..:|   ...|||         :...::..:|.::.
Human   191 CVGHYNHRYFFSFCFFMTLGCVY---CSYGSWDLFREAYAAIEKMKQLDKNKLQAVANQTYHQTP 252

  Fly   184 ------QLRMIHS--VILMLVSALFGLFVTAIMVDQLHAILYD--ETAVE---------AIQQKG 229
                  :.||.|.  |.|..:.:...|.:.|:.|  .||:|..  ||::|         .:|.||
Human   253 PPTFSFRERMTHKSLVYLWFLCSSVALALGALTV--WHAVLISRGETSIERHINKKERRRLQAKG 315

  Fly   230 TYRPNRRKYQLLAD--VF-----GRGHPALWLLPCTSLNHAS 264
            ....|...|..|.:  ||     ||......|||.:.|.|.:
Human   316 RVFRNPYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGN 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	48/168 (29%)
ZDHHC16	NP_115703.2	DHHC	156..305	CDD:396215	47/153 (31%)