DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dnz1 and Zdhhc4

DIOPT Version :9

Sequence 1:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_082655.1	Gene:	Zdhhc4 / 72881	MGIID:	1920131	Length:	343	Species:	Mus musculus

Alignment Length:	204	Identity:	54/204 - (26%)
Similarity:	85/204 - (41%)	Gaps:	59/204 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RDPCGIACLVVTYGAVLYAD-----------------YVVIRWIILTTMPGSLWMSFHVVLFNTV 52
            |.|..|...::..|.| ||:                 |:::.:::|:.              |.|
Mouse    64 RHPTFIVLHLLLQGLV-YAEYTCEVFGYCRELEFSLPYLLLPYVLLSV--------------NLV 113

  Fly    53 VFLLAMSHSKAVFSDPGTVPLPANR------LDFSDLHTTNKNNPPPGNGHSSEWTVCTRCETYR 111
            .|.|..:      ::|||: ..||.      ..|.|:..       |.|..      |..|:..:
Mouse   114 FFTLTCA------ANPGTI-TKANESFLLQVYKFDDVMF-------PKNSR------CPTCDLRK 158

  Fly   112 PPRAHHCRICKRCIRRMDHHCPWINNCVGERNQKYFLQFLIYVALLSLYSIALIVGSWVWPCEEC 176
            |.|:.|||:|.||:.|.||||.|:|||:|..|.:|||.:|:.:. .|..:||.:..:::......
Mouse   159 PARSKHCRLCDRCVHRFDHHCVWVNNCIGAWNTRYFLIYLLTLT-ASAATIATVTAAFLLRLVTV 222

  Fly   177 SQNVIETQL 185
            |....||.|
Mouse   223 SDLYQETYL 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	32/89 (36%)
Zdhhc4	NP_082655.1	DHHC	151..292	CDD:396215	32/82 (39%)
Zdhhc4	NP_082655.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9NPG8	340..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848324
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740