DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dnz1 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001028745.1	Gene:	Zdhhc6 / 66980	MGIID:	1914230	Length:	413	Species:	Mus musculus

Alignment Length:	264	Identity:	72/264 - (27%)
Similarity:	122/264 - (46%)	Gaps:	60/264 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GIACLVVTYGAVLYADYVVIRWIILTTMPGSLWMSFHVVLFNTVVFLLAMSHSKAVFSDPGTVPL 73
            |:..:..|...:   |.|:..|.:.|| .||  ::| ::|.|..|.:| .::..|:|:.||.||
Mouse    29 GVIAICSTMAMI---DSVLWYWPLHTT-GGS--VNF-IMLINWTVMIL-YNYFNAMFAGPGFVP- 84

  Fly    74 PANRLDFSDLHTTNKNNPPPGNGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMDHHCPWINNC 138
                          :...|..:..|.....|..|:.|:.||:||||.|.||:.:|||||||||||
Mouse    85 --------------RGWKPEKSQDSMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMDHHCPWINNC 135

  Fly   139 VGERNQKYFLQFLI----------YVALLSLYSIALIVGSWVWPCEECSQNVIETQLR------- 186
            .|.:|...|..||:          ::.::::|:......|:.|       |.::..:.
Mouse   136 CGHQNHASFTLFLLLAPLGCTHAAFIFVMTMYTQLYNRLSFGW-------NTVKIDMSAARRDPP 193

  Fly   187 -MIHSVILMLVSALFGLFV---TAIMVD-----QLHAILYDETAVEA-IQQKGTYRPNRRKYQLL 241
             ::...:....:.||.|.:   |.|.|.     |:..||.::|::|: |::|.   .:|.:|..|
Mouse   194 PIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIKIILRNKTSIESWIEEKA---KDRIQYYQL 255

  Fly   242 ADVF 245
            .:||
Mouse   256 DEVF 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	45/157 (29%)
Zdhhc6	NP_001028745.1	DHHC	95..241	CDD:366691	44/152 (29%)
		SH3_2	317..396	CDD:369452
		Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9H6R6	410..413
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820