Protein Alignment Dnz1 and ZDHHC6

DIOPT Version :9

• Sequence 1: NP_477449.1
• Gene: Dnz1 / 34503
• FlyBaseID: FBgn0027453
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_001338011.1
• Gene: ZDHHC6 / 64429
• HGNCID: 19160
• Length: 413
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 74/260 - (28%)
• Similarity: 120/260 - (46%)
• Gaps: 52/260 - (20%)

  Fly     9 GIACLVVTYGAVLYADYVVIRWIILTTMPGSLWMSFHVVLFNTVVFLLAMSHSKAVFSDPGTVPL 73
            |:..:..|...:   |.|:..|.:.|| .||  ::| ::|.|..|.:| .::..|:|..||.|||
Human    29 GVIAICSTMAMI---DSVLWYWPLHTT-GGS--VNF-IMLINWTVMIL-YNYFNAMFVGPGFVPL 85

  Fly    74 ---PANRLDFSDLHTTNKNNPPPGNGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMDHHCPWI 135
               |....|...|.                  .|..|:.|:.||:||||.|.||:.:||||||||
Human    86 GWKPEISQDTMYLQ------------------YCKVCQAYKAPRSHHCRKCNRCVMKMDHHCPWI 132

  Fly   136 NNCVGERNQKYFLQFLI----------YVALLSLYSIALIVGSWVWPCEECSQNVIETQ-LRMIH 189
            |||.|.:|...|..||:          ::.::::|:......|:.|...:...:..... |.::.
Human   133 NNCCGYQNHASFTLFLLLAPLGCIHAAFIFVMTMYTQLYHRLSFGWNTVKIDMSAARRDPLPIVP 197

  Fly   190 SVILMLVSALFGLFV---TAIMVD-----QLHAILYDETAVEA-IQQKGTYRPNRRKYQLLADVF 245
            ..:....:.||.|.:   |.|.|.     |:..||.::|::|: |::|.   .:|.:|..|.:||
Human   198 FGLAAFATTLFALGLALGTTIAVGMLFFIQMKIILRNKTSIESWIEEKA---KDRIQYYQLDEVF 259

  Fly   246  245
            Human   260  259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	44/150 (29%)
ZDHHC6	NP_001338011.1	DHHC	95..241	CDD:396215	44/163 (27%)
		SH3	317..394	CDD:418401
		Di-lysine motif. /evidence=ECO:0000269|PubMed:21926431	410..413

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820