DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dnz1 and zgc:77880

DIOPT Version :9

Sequence 1:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_957185.1	Gene:	zgc:77880 / 393865	ZFINID:	ZDB-GENE-040426-1901	Length:	297	Species:	Danio rerio

Alignment Length:	287	Identity:	140/287 - (48%)
Similarity:	182/287 - (63%)	Gaps:	34/287 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RDPCGIACLVVTYGAVLYADYVVIRWIILTTMPGSLWMSFHVVLFNTVVFLLAMSHSKAVFSDPG 69
            |||||..||::||.:|.|||||||:::::....||:|.:.|..:||.::|||...||||||||||
Zfish     8 RDPCGFICLILTYFSVFYADYVVIQYVLIPAYSGSVWCTLHGSVFNIILFLLLACHSKAVFSDPG 72

  Fly    70 TVPLPANRLDFSDLHT-TNKNNPPPGNGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMDHHCP 133
            .||||...:|||||.: :|:.|.....|    ||||:||||||||||||||:|:|||||||||||
Zfish    73 MVPLPETAIDFSDLRSQSNRLNDRGCEG----WTVCSRCETYRPPRAHHCRVCQRCIRRMDHHCP 133

  Fly   134 WINNCVGERNQKYFLQFLIYVALLSLYSIALIVGSWVWPC--------EECSQNVIETQLRMIHS 190
            ||||||||.|||||:|||.|..:.||||:||:|.:|||..        |:..:......|.:.|.
Zfish   134 WINNCVGELNQKYFIQFLFYTGMASLYSMALVVSAWVWRIRSEREGDEEKEGEEAPSKHLIVAHY 198

  Fly   191 VILMLVSALFGLFVTAIMVDQLHAILYDETAVEAIQQK------GTYRPN------RRKYQLLAD 243
            :||::.|.|||:||..|..|||.:|:.|||.:|.::.:      ...:|:      :.|..||.:
Zfish   199 IILLVESILFGVFVLVIFYDQLVSIITDETPIEQMRNRLIKDKANNSQPSHVAHTRKPKIALLRE 263

  Fly   244 VFGRGHPALWLLPCTSLNHASRYHDTP 270
            |||||....||.|         .|.||
Zfish   264 VFGRGSILCWLFP---------LHSTP 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	77/138 (56%)
zgc:77880	NP_957185.1	zf-DHHC	12..>164	CDD:303066	95/155 (61%)
zgc:77880	NP_957185.1	zf-DHHC	103..235	CDD:279823	75/131 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593745
Domainoid	1	1.000	169	1.000	Domainoid score	I3775
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H76489
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2891
OMA	1	1.010	-	-		QHG48042
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	1	1.000	-	-		FOG0001671
OrthoInspector	1	1.000	-	-		oto40013
orthoMCL	1	0.900	-	-		OOG6_107900
Panther	1	1.100	-	-	LDO	PTHR22883
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4075
SonicParanoid	1	1.000	-	-		X8661
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800