DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dnz1 and zdhhc16b

DIOPT Version :9

Sequence 1:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	XP_009304660.1	Gene:	zdhhc16b / 393316	ZFINID:	ZDB-GENE-040426-1301	Length:	382	Species:	Danio rerio

Alignment Length:	329	Identity:	82/329 - (24%)
Similarity:	124/329 - (37%)	Gaps:	118/329 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVFIRDPCGIACLVVTY-GAVLYADYVVIRWIILTTMPGSLWMSFHVVLFNTVVFLLAMSHSKAV 64
            :||:       |||:.. .:|:...|:.:..||.::.| ..|:.:|:...:..:.::...:.||.
Zfish    79 VVFV-------CLVMALTSSVVVIVYLCVLPIIFSSYP-VYWILWHLCYGHWNLLMVVFHYYKAT 135

  Fly    65 FSDPGTVPLPANRLDFSDLHTTNKNNPPPGNGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMD 129
            .:.||..|     .:.:|:.|.               |:|.:|...:|.|.|||.||.|||.:||
Zfish   136 TTQPGFPP-----QEKTDIPTV---------------TICKKCIVPKPARTHHCSICNRCILKMD 180

  Fly   130 HHCPWINNCVGERNQKYFLQFLIYVALLSLYSIALIVGSWVWPCEECS----------QNVIET- 183
            |||||:|||||..|.:||..|.:::.:               .|..||          .|.||:
Zfish   181 HHCPWLNNCVGHFNHRYFFSFCLFMTM---------------GCVYCSISAKDMFLDAYNAIESG 230

  Fly   184 -------------------------------------QLRMIHSVILMLVSALFGLFVTAIMVDQ 211
                                                 |.||:|..::.|......:.|....:..
Zfish   231 RYKGGASQGEAVPGAGLIYISFQHQSSYQTPPPAFTHQERMVHKSLVYLWVLTSSVAVALGALTL 295

  Fly   212 LHAILY--DETAVEAIQQKGTYRPNRRKYQLLADVF------GR------------GHPALW--L 254
            .||||.  .||:||    :...|..||:.:|...:|      ||            |...||  |
Zfish   296 WHAILITRGETSVE----RHINRKERRRLKLRGKLFRNPYHHGRINNWRIFFGVEKGSDWLWRVL 356

  Fly   255 LPCT 258
            ||.|
Zfish   357 LPST 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	49/180 (27%)
zdhhc16b	XP_009304660.1	zf-DHHC	83..>206	CDD:327686	46/143 (32%)
zdhhc16b	XP_009304660.1	zf-DHHC	154..310	CDD:307600	48/174 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820