DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dnz1 and Zdhhc5

DIOPT Version :9

Sequence 1:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001034427.1	Gene:	Zdhhc5 / 362156	RGDID:	1589737	Length:	715	Species:	Rattus norvegicus

Alignment Length:	208	Identity:	66/208 - (31%)
Similarity:	99/208 - (47%)	Gaps:	26/208 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 TMPG-SLWMSFHVVLFNTVVFLLAMSH-SKAVFSDPGTVPLPANRLDFSD-----LHTTNKNNPP 92
            |.|| ||.:|..|.::|.::||..::: |.|.|.|||..|......|..|     |:.|.:..
  Rat    35 TCPGLSLDVSPAVPIYNAIMFLFVLANFSMATFMDPGIFPRAEEDEDKEDDFRAPLYKTVEIK-- 97

  Fly    93 PGNGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMDHHCPWINNCVGERNQKYFLQFLIYVA-- 155
             |.....:|  |..|..|||||..||.:|..|:...||||||:|||:|.||.:||..||:.:.
  Rat    98 -GIQVRMKW--CATCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTAH 159

  Fly   156 LLSLYSIALIVGSWVWPCEECSQNVIETQLRMIHSVILMLVSALFGLFVTAIM-VDQLHAILYDE 219
            ::.::...|:   :|. |.      || :|..:.:.:.|.|..:.|||...:. :...|.:|...
  Rat   160 IMGVFGFGLL---YVL-CH------IE-ELSGVRTAVTMAVMCVAGLFFIPVAGLTGFHVVLVAR 213

  Fly   220 TAVEAIQQKGTYR 232
            ......|..|.:|
  Rat   214 GRTTNEQVTGKFR 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	42/133 (32%)
Zdhhc5	NP_001034427.1	zf-DHHC	99..224	CDD:279823	42/137 (31%)
Zdhhc5	NP_001034427.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..715
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810