DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dnz1 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001032741.1	Gene:	Zdhhc6 / 361771	RGDID:	1304657	Length:	413	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	74/267 - (27%)
Similarity:	122/267 - (45%)	Gaps:	66/267 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GIACLVVTYGAVLYADYVVIRWIILTTMPGSLWMSFHVVLFNTVVFLLAMSHSKAVFSDPGTVP- 72
            |:..:..|...:   |.|:..|.:.|| .||  ::| ::|.|..|.:| .::..|:|:.||.||
  Rat    29 GVIAICSTMAMI---DSVLWYWPLHTT-GGS--VNF-IMLINWTVMIL-YNYFNAMFAGPGFVPR 85

  Fly    73 --LPANRLDFSDLHTTNKNNPPPGNGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMDHHCPWI 135
              .|.|..|                  |.....|..|:.|:.||:||||.|.||:.:||||||||
  Rat    86 GWKPENPQD------------------SMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMDHHCPWI 132

  Fly   136 NNCVGERNQKYFLQFLI----------YVALLSLYSIALIVGSWVWPCEECSQNVIETQLR---- 186
            |||.|.:|...|..||:          ::.::::|:......|:.|       |.::..:.
  Rat   133 NNCCGHQNHASFTLFLLLAPLGCTHAAFIFVMTMYTQLYNRLSFGW-------NTVKIDMSAARR 190

  Fly   187 ----MIHSVILMLVSALFGLFV---TAIMVD-----QLHAILYDETAVEA-IQQKGTYRPNRRKY 238
                ::...:....:.||.|.:   |.|.|.     |:..||.::|::|: |::|.   .:|.:|
  Rat   191 DPPPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIKIILRNKTSIESWIEEKA---KDRIQY 252

  Fly   239 QLLADVF 245
            ..|.:||
  Rat   253 YQLDEVF 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	45/157 (29%)
Zdhhc6	NP_001032741.1	DHHC	95..241	CDD:396215	44/152 (29%)
Zdhhc6	NP_001032741.1	SH3_2	317..394	CDD:400139
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820