Protein Alignment Dnz1 and ZDHHC20

DIOPT Version :10

• Sequence 1: NP_477449.1
• Gene: Dnz1 / 34503
• FlyBaseID: FBgn0027453
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_001316988.1
• Gene: ZDHHC20 / 253832
• HGNCID: 20749
• Length: 365
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 81/307 - (26%)
• Similarity: 129/307 - (42%)
• Gaps: 96/307 - (31%)

  Fly    14 VVTYGAVLYADYVVIRWIILTTMPGSLWMSFHVV-------LF------NTVVFLLAM------- 58
            ||.:..||:..:||:            |..:..|       :|      .|||:|:|.
Human    13 VVGWVPVLFITFVVV------------WSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMF 65

  Fly    59 --SHSKAVFSDPGTVPLPANRL------------DFSD---------------LHTTNKNNPPPG 94
              |:...:|:.|.:   |:...            :||.               ::||
Human    66 VWSYWMTIFTSPAS---PSKEFYLSNSEKERYEKEFSQERQQEILRRAARALPIYTT-------- 119

  Fly    95 NGHSSEWTV--CTRCETYRPPRAHHCRICKRCIRRMDHHCPWINNCVGERNQKYFLQFLIYVALL 157
               |:..|:  |.:|:..:|.|||||..|..||.:|||||||:|||||..|.|:||.||:|..|.
Human   120 ---SASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLY 181

  Fly   158 SLYSIALIVGSWV--WPCEECSQNVIETQLRMIHSVILMLVSALFGLFVTAIMVDQLHAILY--D 218
            .|:..|.::..::  |     :..:.:|:.: .|.:.|..|||:|  |::.:.:...|..|.  :
Human   182 CLFVAATVLEYFIKFW-----TNELTDTRAK-FHVLFLFFVSAMF--FISVLSLFSYHCWLVGKN 238

  Fly   219 ETAVEAIQQKG-TYRPNRRKYQL-----LADVFGRGHPALWLLPCTS 259
            .|.:|:.:... :|.|:...:.|     ...||| .....||||..|
Human   239 RTTIESFRAPTFSYGPDGNGFSLGCSKNWRQVFG-DEKKYWLLPIFS 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	48/136 (35%)
ZDHHC20	NP_001316988.1	DHHC	16..301	CDD:418707	79/304 (26%)