DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dnz1 and Zdhhc14

DIOPT Version :9

Sequence 1:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_666185.3	Gene:	Zdhhc14 / 224454	MGIID:	2653229	Length:	489	Species:	Mus musculus

Alignment Length:	235	Identity:	60/235 - (25%)
Similarity:	109/235 - (46%)	Gaps:	34/235 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 IILTTMPGSLWMSFH-----------VVLFNTVVFLLAM-SHSKAVFSDPGTVPLPA-------- 75
            :||..:...|:.:|.           :.:...::|...| :..:..|||||.:|...
Mouse    68 LILILVTSGLFFAFDCRYLAEKITPAIPVVGGILFFFVMGTLLRTSFSDPGVLPRATPDEAADLE 132

  Fly    76 NRLDFSDLHTTNKNNPPPG------NGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMDHHCPW 134
            .::|.::..::....|||.      ||.:.:...|..|:.:|||||.||.:|..|:.:.||||||
Mouse   133 RQIDIANGTSSGGYRPPPRTKEVVINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVEQFDHHCPW 197

  Fly   135 INNCVGERNQKYFLQFLIYVALLSLYSIALIVGSWVWPCEECSQNVIETQLRMIHSVILMLVSAL 199
            :.||||:||.::|..|::.::.|:::..|.::...:   ....|......|:...:.:|..|...
Mouse   198 VGNCVGKRNYRFFYMFILSLSFLTVFIFAFVITHVI---HRSQQKGFLDALKDSPASVLEAVICF 259

  Fly   200 FGLFVTAIMVDQLHAILY--DETAVEAIQQKGTYRPNRRK 237
            |.:: :.|.:...|..|.  ::|..|.|  ||::...|.|
Mouse   260 FSVW-SIIGLSGFHTYLISSNQTTNEDI--KGSWSNKRGK 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	38/132 (29%)
Zdhhc14	NP_666185.3	zf-DHHC	164..289	CDD:307600	39/130 (30%)
Zdhhc14	NP_666185.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	434..454
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810