DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dnz1 and zdhhc23a

DIOPT Version :9

Sequence 1:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	XP_021327278.1	Gene:	zdhhc23a / 100150190	ZFINID:	ZDB-GENE-060526-38	Length:	434	Species:	Danio rerio

Alignment Length:	197	Identity:	63/197 - (31%)
Similarity:	88/197 - (44%)	Gaps:	24/197 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LPANRLDFSDLHTTNKNNPPPGNGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMDHHCPWINN 137
            |..||.....|.|..:|......|.......|..|:..|||||.|||||..|:.||||||.|||:
Zfish   196 LATNRSTNLTLDTDLRNGVSHLKGEKDVKKKCPVCQLVRPPRAGHCRICGACVLRMDHHCVWINS 260

  Fly   138 CVGERNQKYFLQFLIYVALLSLYSIALIVGSWVWPCEE-------CS--QNVIETQLRMI---HS 190
            |||:.|.:.|:..|:...|.|.|.|:|::.| :.|.:.       |.  .|...|.|...   :|
Zfish   261 CVGQANHRQFILTLLLFLLTSFYGISLVLRS-ICPKQSLFTAMLYCPGVYNQYSTALCFTCVWYS 324

  Fly   191 VILMLVSALFGLFVTAIMVDQLHAILYDETAVEAIQQKGTYRPNRRKYQLLADVFG---RGHPAL 252
            ||  :...|..||:..|:  .:...:.:..|..|::.|    ..||::..|....|   ||....
Zfish   325 VI--ITGGLLHLFILQII--NVSCNVTEREAQIALRNK----TGRRRFCGLVVETGDHSRGFLQN 381

  Fly   253 WL 254
            |:
Zfish   382 WI 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	48/142 (34%)
zdhhc23a	XP_021327278.1	zf-DHHC	224..352	CDD:307600	46/132 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810