DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dnz1 and zdhhc22

DIOPT Version :9

Sequence 1:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	XP_001340992.2	Gene:	zdhhc22 / 100000886	ZFINID:	ZDB-GENE-131127-476	Length:	280	Species:	Danio rerio

Alignment Length:	277	Identity:	74/277 - (26%)
Similarity:	105/277 - (37%)	Gaps:	78/277 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 AVLYADYVVIRWIILTTMPGSLWMSFHVVLFNTVVFLLAMSHSKAVFSDPGTVP-------LPAN 76
            |..||..||.             .:.|.:||...:|     .|..|..:|..:.       |..|
Zfish    17 AYFYAATVVT-------------FALHFLLFTPTIF-----QSSDVTINPAMLAHISIFLFLMGN 63

  Fly    77 RLDFSDLHTTNKNNPPPGNGHSSEWTVCTRCETYRPPR---------AHHCRICKRCIRRMDHHC 132
            .|   ..:.....||    ..|:..||...|....|.|         .|.|::||:.|.:.||||
Zfish    64 AL---GNYIMTIRNP----SESANETVIPVCSPDCPDRIDAHYLLNGRHFCKVCKKVILKRDHHC 121

  Fly   133 PWINNCVGERNQKYFLQFLIYVALLSLYSIALIVG----------SWVWPCEECSQNVIETQ--- 184
            .:..||:|.||.:||:.|.||.:...|||  |::|          |:..|....:...:.|.
Zfish   122 FFTGNCIGNRNMRYFIMFSIYTSSSCLYS--LVIGVAYLTIEYSISFENPLTFLTLLPLSTGYFF 184

  Fly   185 LRMIHSVILMLVSALF-----GLFVTAIMVDQLHAILYDETAVEAIQQ------KGTYRPNRRKY 238
            |.:|..:...||..|:     ||........||..:...:|..| :|:      :||:|.|
Zfish   185 LGLISGLQFFLVIMLYIWLGIGLVSVGFCCQQLLLVARGQTWCE-LQKGQLSECRGTWRAN---- 244

  Fly   239 QLLADVFGRGHPALWLL 255
              |.|||| .|   |:|
Zfish   245 --LTDVFG-SH---WVL 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	45/163 (28%)
zdhhc22	XP_001340992.2	zf-DHHC	105..233	CDD:307600	39/130 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910