DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-3 and SmydA-1

DIOPT Version :9

Sequence 1:	NP_001260366.1	Gene:	SmydA-3 / 34502	FlyBaseID:	FBgn0262599	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_610944.1	Gene:	SmydA-1 / 36581	FlyBaseID:	FBgn0033917	Length:	513	Species:	Drosophila melanogaster

Alignment Length:	513	Identity:	145/513 - (28%)
Similarity:	237/513 - (46%)	Gaps:	47/513 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SVNRTAVQW---SPVC-----------GRYLVAKGAIRGHGLLIEELPFAVGPKCNGPVVCLGCY 58
            ||......|   .|.|           ||:|||...|:.:.::::|.|...||......|||||.
  Fly    25 SVQHQKQDWKVHKPSCHPFKIAHNEQLGRHLVATRTIKPYEIVLKEAPLVRGPAQISAPVCLGCL 89

  Fly    59 EPNPDPEEELCSECGWPLC-VECAQQADNAHFRLECSQLKDARARFFRLPSGSRHCPQLDCIMPL 122
            ......:...|.:|||||| .||....::   :.||...||...:......|..| |...|:..:
  Fly    90 NGIEAEDHIECEQCGWPLCGPECKSLDEH---KAECGLTKDRGQKVNVQEFGGPH-PLYTCLSTV 150

  Fly   123 RVLLAKEANPERWDNEVAPMEHHKEERQRDADVWHADRVNIAQYLRGPCQLANRFSEELIMQVVG 187
            |.||..|.:.|: .::...:| ..|..:|.::.|.||.|:|.|::....: ..:|:||.||:.||
  Fly   151 RCLLIGETSTEK-ASKFQDLE-SLESTRRGSNQWKADLVSIGQFIPKFFK-TQKFTEEEIMKAVG 212

  Fly   188 VLEVNAFEARSPKGYPLRCLFPYTGILAHN-CVPNTSRSIYPSEGYKIRLRAMVDLEEGQPLHHS 251
            .|::|..|.  |...|......||.....| |:||.::| :...|:.| |.|..::::...|...
  Fly   213 ALQINGHEV--PTTDPSHVAVFYTASFTENSCLPNLAKS-FNKNGHCI-LWAPREIKKNAHLSIC 273

  Fly   252 YTYTLDGTAQRQKHLKQGKFFTCQCERCLDPTELGTHFSSLKC--GQCAEGFQVPRQPTEPDTSW 314
            |:..:.|||.||:||.|.|.|.|.||||:|.|||.|::|::||  .||. |..:|.:..|.:.||
  Fly   274 YSDAMWGTADRQRHLMQTKLFKCACERCVDVTELDTNYSAIKCEDRQCG-GLMLPTKADEWNGSW 337

  Fly   315 NCANCGSDTSNADALAMLQSLQSEVNAVQALPMAAKRLEEIERLLRKYKSLLHPLHFIATGLRQL 379
            .|..|...........:|:....::.:::      |..|...:.|:.|:..|.|.||..:.::.|
  Fly   338 RCRECHKQVQKHYVERILERAGKDIQSME------KIAENGLKYLKHYEKWLPPQHFHMSEIKIL 396

  Fly   380 LIEMYGRVQGYEMVQLPDHQLERKAELCRQVLRVLNTFEPGLSRTRAMNLYELHVPLVLLAKSGF 444
            |:::..:.| .|::.:||.:|..|....|:::.:.....|...||.....:|||..:....:...
  Fly   397 LVQLLAKDQ-KELMVIPDDRLLLKLNFARELVELYEKLTPCEVRTLGTLCFELHSAIAEQTRRVA 460

  Fly   445 IAGKLKGGELRARLVDAIDLLKECVEILEFEDKSSQEGVLCVVAKQALKQLTLSVEGL 502
            :...|..   :.||.:::..:.:||..|::|.....||       ..|||..::.:.|
  Fly   461 LETSLSP---KDRLEESLFYVDKCVNYLKYESDIFIEG-------HVLKQAKINRDAL 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-3	NP_001260366.1	SET	<207..252	CDD:250181	12/45 (27%)
SmydA-1	NP_610944.1	zf-MYND	4..40	CDD:280009	4/14 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I1875
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46455
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.970