DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-3 and SmydA-5

DIOPT Version :9

Sequence 1:	NP_001260366.1	Gene:	SmydA-3 / 34502	FlyBaseID:	FBgn0262599	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_610202.3	Gene:	SmydA-5 / 35538	FlyBaseID:	FBgn0033061	Length:	553	Species:	Drosophila melanogaster

Alignment Length:	515	Identity:	154/515 - (29%)
Similarity:	230/515 - (44%)	Gaps:	100/515 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GRYL-VAKGAIRGHGLLIEELPFAVGPK----------CNGPVVCLGCYEPNPDPEEELCSECGW 74
            |||| |.:....|..:.||| |..||||          .|.|  |:|||.|....:.: |..|.|
  Fly    55 GRYLKVTQNIAAGQIVFIEE-PLVVGPKWYLSDADKEASNVP--CVGCYTPCRLGKHQ-CRRCRW 115

  Fly    75 PLCVECAQQADNAHFRLECSQLK---------DARA--RFFRLPSGSRHCPQLDCIMPLRVLLAK 128
            |:|     .|...|..:|||.|.         |||:  .:||   |       |.::.|:.||.:
  Fly   116 PVC-----SAGCKHESMECSVLSLGSGSPTRADARSLNDYFR---G-------DALLVLKCLLLQ 165

  Fly   129 EANPERWDNEVAPMEHHKEERQRDADVWHADRVNIAQYL--RGPCQL----ANRFSE---ELIMQ 184
            ..:|.:| :.:..|:.|:||| :..|::......:..||  |..|:|    .|..::   |::.:
  Fly   166 RQSPTKW-SALLEMQSHEEER-KGTDLYEEAEKRVVTYLQKRFLCRLKQTNPNLLTDCGPEMLHR 228

  Fly   185 VVGVLEVNAFEARSPKGYPLRCLFPYTGILAHNCVPNTSRSIYPSEGYKIRLRAMVDLEEGQPLH 249
            :.|::|.|......|.|..|..||....::.|.|.||.... :.::..::.:||..||.:|..|.
  Fly   229 LCGIIETNFMVIELPSGVELSGLFRQACMMEHACQPNCDFQ-FDNKTQQVAVRAGCDLRKGDHLR 292

  Fly   250 HSYTYTLDGTAQRQKHLKQGKFFTCQCERCLDPTELGTHFSSLKC----GQCAEGFQVPRQPTEP 310
            .:||..|.||..||.||:..|.|:|:|.|||||||.||:.|:|.|    .|...|..:|..|.:.
  Fly   293 ITYTNILWGTQLRQHHLRLTKHFSCRCSRCLDPTEYGTYISALTCLGDVNQTCGGTHLPVDPLDE 357

  Fly   311 DTSWNCANCGSDTSNADALAMLQSLQSEVNAVQALPMAAKRLEEIERLLRKYKSLLHPLHFIATG 375
            :|.|.|..|......| .:|.|||..:|  .|:.|........::|.||.:...:|||.||....
  Fly   358 NTQWKCDTCPMIVDGA-YVAELQSHMTE--QVEGLLAGCPSANQVELLLARLTHMLHPNHFHTFN 419

  Fly   376 LRQLLIEMYGRVQGYEMVQLPDHQLERKAELCRQVLRVLNTFEP--------------------- 419
            |:..||::||...|.|:..|.:.|||||..||.::..|....:|
  Fly   420 LKHTLIQLYGNEAGLELGVLSNTQLERKLRLCGELYNVCRRLDPYSIKLAIYVTVILIEVAHTLQ 484

  Fly   420 --------------GLSRTRAMNLYELHVPLVLLAKSGFIAGKLKGGELRARLVDAIDLL 465
                          ||:::|   |.|.|  :||..:...:|||....:|:..:.:...|:
  Fly   485 EQARRAPAEGTSLLGLAQSR---LREAH--MVLEKEQESVAGKKLNEKLQMEIFECEKLI 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-3	NP_001260366.1	SET	<207..252	CDD:250181	12/44 (27%)
SmydA-5	NP_610202.3	zf-MYND	7..43	CDD:280009
SmydA-5	NP_610202.3	SET	185..295	CDD:279228	27/111 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I1875
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46455
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2203
	6	5.970