DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-3 and SmydA-4

DIOPT Version :9

Sequence 1:	NP_001260366.1	Gene:	SmydA-3 / 34502	FlyBaseID:	FBgn0262599	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_572675.1	Gene:	SmydA-4 / 32034	FlyBaseID:	FBgn0030257	Length:	532	Species:	Drosophila melanogaster

Alignment Length:	491	Identity:	163/491 - (33%)
Similarity:	256/491 - (52%)	Gaps:	20/491 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VQWSPVCGRYLVAKGAIRGHGLLIEELPFAVGPKCNGPVVCLGCYEP-NPDPEEELCSECGWPLC 77
            |:.|.:.||||||...:.....||.|.|.|:||..:|..||||||.| :...::..|..|.||||
  Fly    51 VEHSDIYGRYLVANRQLEAGETLIREEPLAIGPCVSGDPVCLGCYHPVSLKADQYRCPGCAWPLC 115

  Fly    78 -VECA-QQADNAHFRLECSQLKDARARFFRL------PSGSRHCPQLDCIMPLRVLLAKEANPER 134
             ..|| .:..:.|...||....:.||....|      |:..|...:|  :|.:|:||.::.:||:
  Fly   116 GSTCAGLKHRHGHTETECQLYAERRAVAGELLTERAGPAEVRDLYEL--VMIVRILLLRQHDPEQ 178

  Fly   135 WDNEVAPMEHHKEERQRDADVWHADRVNIAQYLRGPCQLANRFSEELIMQVVGVLEVNAFEARSP 199
            : ..:|.||.|.|||:::|.:|......:.|.||...||.:..:|: :.:|.|:|:||.||. ..
  Fly   179 F-ALIARMESHTEERRQNAVLWRHYEEKVVQRLRVTWQLEDLEAEQ-VHEVCGILDVNCFEI-GQ 240

  Fly   200 KGYPLRCLFPYTGILAHNCVPNTSRSIYPSEGYKIRLRAMVDLEEGQPLHHSYTYTLDGTAQRQK 264
            .|...|.|:|...:|||:|.|||:.:..|| .::|.||....:.|.:.|..||.|||.||.:|:.
  Fly   241 NGAKARTLYPSAFLLAHDCTPNTAHTDDPS-SFEILLRTSRRVREREALTLSYAYTLQGTLKRRA 304

  Fly   265 HLKQGKFFTCQCERCLDPTELGTHFSSLKCGQCAEGFQVPRQPTEPDTSWNCANCGSDTSNADAL 329
            .:.:||.|.|.|.||.||.||||..|:|.|..|..|......|.:....|.|..|.......:..
  Fly   305 FMHEGKLFWCCCRRCSDPRELGTDCSALVCATCRTGSVRAVDPLQQTGDWACDRCAHKMGATEVE 369

  Fly   330 AMLQSLQSEVNAVQALPMAAKRLEEIERLLRKYKSLLHPLHFIATGLRQLLIEMYGRVQGYEMVQ 394
            ..|..:.:::..:.     ...:..:|..|.:|:.:|.|.|::....:..|.::|||.:||.:.|
  Fly   370 RQLDRINNDLEDID-----VHDIPGLENFLLRYRDVLRPNHYLLLSAKYSLCQIYGRTEGYLLPQ 429

  Fly   395 LPDHQLERKAELCRQVLRVLNTFEPGLSRTRAMNLYELHVPLVLLAKSGFIAGKLKGGELRARLV 459
            :....:.||...||:.|.:::..:|||:|.|.:.:||||.|:::||:|.|.:|::...|.:.||.
  Fly   430 MSPEDIARKESYCREFLEIVDVLDPGLTRLRGLIMYELHAPVMVLAQSAFQSGQISRQEFQRRLK 494

  Fly   460 DAIDLLKECVEILEFEDKSSQEGVLCVVAKQALKQL 495
            :.:.||:...:||..|.:.|.|..:...|..||.::
  Fly   495 EVVKLLQVSRDILLMEPEGSTENAMGQAAADALSKM 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-3	NP_001260366.1	SET	<207..252	CDD:250181	16/44 (36%)
SmydA-4	NP_572675.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I1875
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D199835at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46455
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2203
	6	5.970