Protein Alignment SmydA-3 and Smyd4

DIOPT Version :9

• Sequence 1: NP_001260366.1
• Gene: SmydA-3 / 34502
• FlyBaseID: FBgn0262599
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001099280.1
• Gene: Smyd4 / 287525
• RGDID: 1307369
• Length: 801
• Species: Rattus norvegicus
• Alignment Length: 611
• Identity: 124/611 - (20%)
• Similarity: 199/611 - (32%)
• Gaps: 199/611 - (32%)

  Fly     3 SPPTLSVNRTAVQWSPVCGRYLVAKGAIRGHGLLIEELPFAVGPKCNGPVVCLGCYEPNPDPEEE 67
            |..:|||:...   .|:.||:|||...|....||::|..|            :....|...|...
  Rat   229 SGASLSVSLCT---DPLKGRHLVATKDILPGELLVKEDAF------------VSVLNPGEMPPLR 278

  Fly    68 LCSECGWPLCV-------------------------------ECAQQADNAHFRLECS------- 94
            .|.|..|...|                               ||.|||.:.:...|||
  Rat   279 HCLENKWDTRVTSADLYCHRCLRHTLATVPCGGCSYAKYCSQECVQQAWDHYHSTECSLGGLLLT 343

  Fly    95 ---------------QLKDARARFFRL---PSGSRHCPQLDCIMPLRVLLAK----------EAN 131
                           :.:|. .|..|:   .:|.:     |..:|....|.|          |.|
  Rat   344 LGVFCHVALRMTLLARFEDV-DRVIRMICDKTGRK-----DTCLPESKDLVKTFGYTNQGESEEN 402

  Fly   132 PE-------------RWDNE-------VAPMEHHKEERQ-------------------------- 150
            .|             :::|.       :...|.|..|.:
  Rat   403 SETCEPSIPGCNVNGKYENNYDAVLSLLPHTEKHSPEHKFICAVSVSALCRQLKATSLQAQTTGL 467

  Fly   151 -------------RDADVW------HADRVNI-AQYLRGPCQLANRFSEELIMQVVGVLEVNAFE 195
                         .|..||      |..::.. ||.:...|...::  |.:|        .|:.:
  Rat   468 KSPRLKAVTPGLCTDLTVWGVAMLQHMLQLQCNAQAITSICYAGSK--ESII--------TNSRQ 522

  Fly   196 ARSPKGYPLRCLFPYTGILAHNCVPNTSRSIYPSEGYKIRLRAMVDLEEGQPLHHSY--TYTLDG 258
            .|...|     :||...:|.|:|.||||.|...:..   .:||...:.:||.:.|.|  ..:..|
  Rat   523 VRLATG-----VFPVVSLLNHSCSPNTSVSFTSTVA---TIRAAQQIAKGQEILHCYGPHESRMG 579

  Fly   259 TAQRQKHLKQGKFFTCQCERCLDPT---ELGTHFSSLKCGQCAEGFQVPRQPTEPDTSWNCAN-- 318
            .|:||:.|....||.|.|..|...|   .:...:.:..|..|       |.|.:.:...:|:|
  Rat   580 VAERQQRLSSQYFFDCSCPACHAETLRAAVAPRWEAFCCNTC-------RVPMQGNDVLSCSNES 637

  Fly   319 CGSDTSNADALAMLQSLQSEVNAVQAL------PMAAKRLEEIERLLRKYKSLLHP-LHFIATGL 376
            |.:..|....::.||.||.:|:..|.|      ..|.::|.|.:|....:.|..|. |..|..||
  Rat   638 CTNSVSRDRLVSRLQDLQQQVHTAQKLLRSDRPEQAIQQLLECQRAAENFLSAEHTVLGEIEDGL 702

  Fly   377 RQLLIEMYGRVQGYEMVQLPDHQLERK-----AELCRQVLRVLNTFEPGLSRTRAMNLYELHVPL 436
            .|....:....|....||.....:|.:     .|:..::.::......||:...|::.. .....
  Rat   703 AQAYATLGDWRQSAAHVQKSLQVVEARHGPSSVEIGHELFKLAQVLFNGLAVPEALDAI-WKAEK 766

  Fly   437 VLLAKSGFIAGKLKG-GELRARLVDA 461
            :||...|..:.:::. .|:|:.|:|:
  Rat   767 ILLVHCGPESDEVQELREMRSCLLDS 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-3	NP_001260366.1	SET	<207..252	CDD:250181	15/44 (34%)
Smyd4	NP_001099280.1	TPR_11	68..132	CDD:290150
		TPR repeat	68..96	CDD:276809
		TPR repeat	101..136	CDD:276809
		zf-MYND	296..335	CDD:280009	5/38 (13%)
		SET	<526..572	CDD:279228	16/53 (30%)
		TPR_12	692..>748	CDD:290160	11/55 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810