Protein Alignment SmydA-3 and set-14

DIOPT Version :10

• Sequence 1: NP_609464.1
• Gene: SmydA-3 / 34502
• FlyBaseID: FBgn0262599
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_496323.1
• Gene: set-14 / 174662
• WormBaseID: WBGene00011068
• Length: 429
• Species: Caenorhabditis elegans
• Alignment Length: 488
• Identity: 100/488 - (20%)
• Similarity: 163/488 - (33%)
• Gaps: 144/488 - (29%)

  Fly    63 DPEEELCSECGWPL-----CVEC---------AQQADNAHFRLECSQLK---------------- 97
            |..|..|::|...:     |..|         .|:||....::||..:|
 Worm    20 DQVESYCNQCLTSMAELKKCSACRRLAYCSQECQRADWKLHKVECKAIKTHNEVANDSIRLVMRI 84

  Fly    98 --------DARARFFRLPSGSRHCPQLDCIMPLRVLLAKEANPERWDNEVAPMEHHKEERQRDAD 154
                    |.....:.:|..:|:...|            |.:|..:|   |..|...:|..:.|.
 Worm    85 AGKLSRNEDGEIEAYYIPGVARNFQNL------------EHHPSSYD---ADEESFVKEYFQFAI 134

  Fly   155 VWHADRVNIAQYLRGPCQLANRFSEELIMQVVGVLEVNAFEARSPKGYPL---RCLFPYTGILAH 216
            ..|.||                   :||..:...:.:|:|...:..|.|:   .|:  ......|
 Worm   135 APHPDR-------------------DLIKLIFQKVSINSFVVGNSTGNPIGVGLCI--KLSAANH 178

  Fly   217 NCVPNTSRSIYPSEGYKIRLRAMVDLEEGQP-----LHHSYTYTLDGTAQRQKHLKQGKFFTCQC 276
            :|.|.|...      |:.|...:|.:....|     ..|||...|.....|:..||:...|.|||
 Worm   179 SCKPLTRVC------YRNRTAMLVPVSSELPSTLEGACHSYIDELMPRDMRRDTLKKKYKFLCQC 237

  Fly   277 ERCLDPTELGTHFSSLKCGQCAEGFQVPRQPTEPDTSWNCANCGSDTSNADALAMLQSLQSEVNA 341
            :.||| .:......:..||.|.:|:...::      :..|..||. |.:.|...:.::.:....|
 Worm   238 DGCLD-EDRNARMEAWTCGICVKGWMRNKE------NGQCELCGW-TMSKDHFELCRTAEEAGIA 294

  Fly   342 VQ------ALPMAAKRLEEIERLLRKYKSLLHP--LHFIATGLRQLLIEMYGRVQGYEMVQLPDH 398
            .:      |:|:..|| ...|:||..::..||.  :|.|.. ||.|.|           ..|...
 Worm   295 ARSRLANDAIPLETKR-NLCEKLLDLFQDTLHDHNVHRIPV-LRCLYI-----------CSLAAQ 346

  Fly   399 QLERKAELCRQVLRVL----NTFEPGLSRTRAMNLYELHVPLVLLAKSGFIAGKLKGGELRARLV 459
            .:...|:....:|.::    ||.:|.:       |::.:....|...:|             ...
 Worm   347 NITAAAKTGGTLLSIMLVYQNTTDPAI-------LFQKYQLAQLFCAAG-------------AKT 391

  Fly   460 DAIDLLKECVEILE---FEDKSSQEGVLCVVAK 489
            .|..||:|..|.||   ..|......|.|::.|
 Worm   392 QATKLLQEIEEPLEKIYTPDSMICRNVYCMILK 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-3	NP_609464.1	SET_SMYD	<192..279	CDD:380997	24/94 (26%)
set-14	NP_496323.1	zf-MYND	26..64	CDD:460312	7/37 (19%)
		SET	75..241	CDD:394802	40/207 (19%)