back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SmydA-3 and Smyd1

DIOPT Version :9

Sequence 1:	NP_001260366.1	Gene:	SmydA-3 / 34502	FlyBaseID:	FBgn0262599	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001153599.1	Gene:	Smyd1 / 12180	MGIID:	104790	Length:	490	Species:	Mus musculus

Alignment Length:	477	Identity:	104/477 - (21%)
Similarity:	190/477 - (39%)	Gaps:	139/477 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 VCLGCYEPNPDPEEEL--CSECGWP-LCVECAQQADNAHFRLECSQLKDARARFFRLPSGSRHCP 114
            ||..|::    .:|:|  |.:|.:. .|....|:....:.:.||:.:|    ::.::|:.:..
Mouse    51 VCHTCFK----RQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECAAIK----KYGKVPNENIR-- 105

  Fly   115 QLDCIMPLRVLLAKE-----------ANPERWDNEVAPMEHHKEERQRDADVWHADRVNIAQYLR 168
                 :..|::...|           .:.:...|.|   ||..||.|::.      ||::..:|:
Mouse   106 -----LAARIMWRVEREGTGLTEGCLVSVDDLQNHV---EHFGEEEQKEL------RVDVDTFLQ 156

  Fly   169 GPCQLANRFSEELIMQVVGVLEVNAFEARSPKGYPLRC----LFPYTGILAHNCVPNTS------ 223
            .....:.:||.:.|..:.||:..|.|.....:|  |:.    :||..|::.|:|.||.:
Mouse   157 YWPPQSQQFSMQYISHIFGVINCNGFTLSDQRG--LQAVGVGIFPNLGLVNHDCWPNCTVIFNNG 219

  Fly   224 -----RSIYPSEGYKIRLRAMVDLEEGQPLHHSYTYTLDGTAQRQKHLKQGKFFTCQCERCL--- 280
                 :|::.:: .:|.|||:..:.||:.|..||...|..:.:|::.||:..:|.|.||.|.
Mouse   220 NHEAVKSMFHTQ-MRIELRALGKISEGEELTVSYIDFLHLSEERRRQLKKQYYFDCSCEHCQKGL 283

  Fly   281 ----------DP-------TEL-----------------GTHFSSLK-CGQCAEGFQVPRQPTEP 310
                      ||       .|:                 |.:...:| |.:|.|    .::|...
Mouse   284 KDDLFLAAKEDPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLE----KQEPVFA 344

  Fly   311 DTSWNCANCGSDTSNADALAMLQSLQSEV-NAVQALPMAAKRLEEIERLLRKYKSLLH------P 368
            ||            |...|.:| |:.||| :.:||...|:   ....|::..|..|.|      .
Mouse   345 DT------------NLYVLRLL-SIASEVLSYLQAYEEAS---HYARRMVDGYMKLYHHNNAQLG 393

  Fly   369 LHFIATGLRQL---LIEM-YGRV-QGYEMVQL---PDHQLERKAELCR----QVLRVL--NTFEP 419
            :..:..||...   .||: :|.: :.|.::.:   |.|.:.:..|..|    ..||:.  |.|..
Mouse   394 MAVMRAGLTNWHAGHIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRMQTEMELRMFRQNEFMY 458

  Fly   420 GLSRTRAMNLYELHVPLVLLAK 441
            ...|..|:|    :.|:.::|:
Mouse   459 HKMREAALN----NQPMQVMAE 476

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.