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Protein Alignment SmydA-3 and SMYD4

DIOPT Version :9

Sequence 1:	NP_001260366.1	Gene:	SmydA-3 / 34502	FlyBaseID:	FBgn0262599	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_443160.2	Gene:	SMYD4 / 114826	HGNCID:	21067	Length:	804	Species:	Homo sapiens

Alignment Length:	501	Identity:	110/501 - (21%)
Similarity:	163/501 - (32%)	Gaps:	178/501 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 PVCGRYLVAKGAIRGHGLLIEELPF--AVGP-----------------KCNGPVVCLGCYEPN-- 61
            |:.||.|||...|....||::|..|  .:.|                 ..||.:.|..|.:..
Human   241 PLKGRCLVATKDILPGELLVQEDAFVSVLNPGELPPPHHGLDSKWDTRVTNGDLYCHRCLKHTLA 305

  Fly    62 --PDPEEELCSECGW-PLC-VECAQQADNAHFRLECS----------------------QLKDAR 100
              |      |..|.: ..| .||.|||...:.|.||.                      ..:|.|
Human   306 TVP------CDGCSYAKYCSQECLQQAWELYHRTECPLGGLLLTLGVFCHIALRLTLLVGFEDVR 364

  Fly   101 ARFFRLPSGSRHCPQL---DCIMPLRVLLAKEANPERWDNEVAPMEHHKEERQRDADV------- 155
            ....:|      |.::   |..:|       |:|     |:|..:.:...|.:::.::
Human   365 KIITKL------CDKISNKDICLP-------ESN-----NQVKTLNYGLGESEKNGNIVETPIPG 411

  Fly   156 -----WHADRVNIA--------------QYLRGPC-------------------------QLANR 176
                 .:.:..|..              ::|...|                         ||...
Human   412 CDINGKYENNYNAVFNLLPHTENHSPEHKFLCALCVSALCRQLEAASLQAIPTERIVNSSQLKAA 476

  Fly   177 FSEELIMQVV--GV--------LEVNA-----FEARSPKG------YPLRC---LFPYTGILAHN 217
            .:.||...|.  ||        |:.||     .:...|||      ..:|.   :||...:|.|:
Human   477 VTPELCPDVTIWGVAMLRHMLQLQCNAQAMTTIQHTGPKGSIVTDSRQVRLATGIFPVISLLNHS 541

  Fly   218 CVPNTSRSIYPSEGYKIRLRAMVDLEEGQPLHHSY--TYTLDGTAQRQKHLKQGKFFTCQCERCL 280
            |.||||.|...:..   .:||...:.:||.:.|.|  ..:..|.|:||:.|:...||.|.|..|
Human   542 CSPNTSVSFISTVA---TIRASQRIRKGQEILHCYGPHKSRMGVAERQQKLRSQYFFDCACPAC- 602

  Fly   281 DPTE-----LGTHFSSLKCGQCAEGFQVPRQPTEPDTSWNCA--NCGSDTSNADAL-AMLQSLQS 337
             .||     .|..:.:..|..|.       .|.:.|....|.  :|.....:.|.| :.||.||.
Human   603 -QTEAHRMAAGPRWEAFCCNSCG-------APMQGDDVLRCGSRSCAESAVSRDHLVSRLQDLQQ 659

  Fly   338 EVNAVQALPMAAKRLEEIERL---LRKYKSLLHPLHF----IATGL 376
            :|...|.|....:....::||   .|..:|.|...|.    ||.||
Human   660 QVRVAQKLLRDGELERAVQRLSGCQRDAESFLWAEHAVVGEIADGL 705

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.