DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment porin and POR2

DIOPT Version :9

Sequence 1:	NP_001033899.1	Gene:	porin / 34500	FlyBaseID:	FBgn0004363	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_012152.3	Gene:	POR2 / 854692	SGDID:	S000001376	Length:	281	Species:	Saccharomyces cerevisiae

Alignment Length:	289	Identity:	71/289 - (24%)
Similarity:	133/289 - (46%)	Gaps:	23/289 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAPPSYSDLGKQARDIFSKG-YNFGLWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVK 64
            ||...::|:.:....:|::. ::.....|::.|.|.:|:.|..........|.:..|:|.::..:
Yeast     1 MALRFFNDISRDVNGLFNRDFFHTNPLSLNISTTTENGVNFTLKAKQGVTEGPIQTSVEGRFYDR 65

  Fly    65 DYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVN 129
            ..|::|::.|:..|.|.|.:.. .::..|.|..:.....||| .||.||.::|..::..|.:.::
Yeast    66 KEGVSLSQSWSNQNRLNTRIEF-SKIAPGWKGDVNAFLTPQS-IKNAKFNLSYAQKSFAARTSID 128

  Fly   130 I----DLKGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFS 190
            |    |..|     |..||::|::.|...|:||..........::||..:::....:.|:.|..:
Yeast   129 ILQPKDFVG-----SVTLGHRGFVGGTDIAYDTAAGLCARYAMSIGYLAREYSFILSTNNRQCAT 188

  Fly   191 GSIFQRTSDKLDVGVQLSWASGT-SNTKFAIGAKYQLDDDASVRAKVNNASQVGLGYQQKLRDGV 254
            .|.||..:..|.||.:.:..|.| ||.......:|..|..:.|:||:.::....|.|::.|...:
Yeast   189 ASFFQNVNRYLQVGTKATLQSKTSSNMNIEFVTRYVPDSISQVKAKIADSGLTTLSYKRNLNKDI 253

  Fly   255 TLTLSTLVDGKNFNA-----GGHKIGVGL 278
            :|.:     |.:|||     ..||.|..|
Yeast   254 SLGV-----GMSFNALQLTEPVHKFGWSL 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
porin	NP_001033899.1	Porin3_VDAC	3..281	CDD:132767	69/287 (24%)
POR2	NP_012152.3	Porin3_VDAC	6..280	CDD:132767	69/284 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344778
Domainoid	1	1.000	108	1.000	Domainoid score	I1419
eggNOG	1	0.900	-	-		E1_KOG3126
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I1354
Isobase	1	0.950	-	0	Normalized mean entropy	S1329
OMA	1	1.010	-	-		QHG51941
OrthoFinder	1	1.000	-	-		FOG0001091
OrthoInspector	1	1.000	-	-		mtm9236
orthoMCL	1	0.900	-	-		OOG6_101484
Panther	1	1.100	-	-	O	PTHR11743
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.710