Protein Alignment porin and VDAC3

DIOPT Version :9

• Sequence 1: NP_001033899.1
• Gene: porin / 34500
• FlyBaseID: FBgn0004363
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: NP_001129166.1
• Gene: VDAC3 / 7419
• HGNCID: 12674
• Length: 284
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 163/280 - (58%)
• Similarity: 215/280 - (76%)
• Gaps: 1/280 - (0%)

  Fly     4 PSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGI-EFNTAGHSNQESGKVFGSLETKYKVKDYG 67
            |:|.||||.|:|:|:|||.||:.|:|||||:.||: ||:|:||:..::||..|:|||||||.:||
Human     5 PTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVMEFSTSGHAYTDTGKASGNLETKYKVCNYG 69

  Fly    68 LTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNIDL 132
            ||.|:||||||||.||::.:::|.|||||:|:..|.|.:|.|:||.|.:|..:.....|:|:||.
Human    70 LTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKRDCFSVGSNVDIDF 134

  Fly   133 KGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRT 197
            .||.|...|||.::|||||||.:|||.:|||:.|||||||...||.|||.||||.||.|||:|:.
Human   135 SGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKV 199

  Fly   198 SDKLDVGVQLSWASGTSNTKFAIGAKYQLDDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLV 262
            ::|::..:.|:|.:|::||:|.|.|||.||...|:.|||||||.:||||.|.||.||.||||.|:
Human   200 NEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALI 264

  Fly   263 DGKNFNAGGHKIGVGLELEA 282
            |||||:|||||:|:|.||||
Human   265 DGKNFSAGGHKVGLGFELEA 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
porin	NP_001033899.1	Porin3_VDAC	3..281	CDD:132767	160/277 (58%)
VDAC3	NP_001129166.1	Porin3_VDAC	5..283	CDD:132767	160/277 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	357	1.000	Domainoid score	I982
eggNOG	1	0.900	-	-		E1_KOG3126
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	366	1.000	Inparanoid score	I2162
Isobase	1	0.950	-	0	Normalized mean entropy	S1329
OMA	1	1.010	-	-		QHG51941
OrthoDB	1	1.010	-	-		D550640at33208
OrthoFinder	1	1.000	-	-		FOG0001091
OrthoInspector	1	1.000	-	-		otm41568
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11743
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1638
SonicParanoid	1	1.000	-	-		X928
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.920