DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment porin and vdac3

DIOPT Version :9

Sequence 1:	NP_001033899.1	Gene:	porin / 34500	FlyBaseID:	FBgn0004363	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	XP_005166800.1	Gene:	vdac3 / 406529	ZFINID:	ZDB-GENE-040426-2380	Length:	319	Species:	Danio rerio

Alignment Length:	280	Identity:	173/280 - (61%)
Similarity:	214/280 - (76%)	Gaps:	1/280 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PPSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGI-EFNTAGHSNQESGKVFGSLETKYKVKDY 66
            ||:|:||||.|:|||||||.||..|||||||:.||: ||.|.|.||.::||..|:||||||||:.
Zfish    39 PPAYADLGKSAKDIFSKGYGFGTVKLDLKTKSQSGVMEFTTGGSSNTDTGKAAGNLETKYKVKEL 103

  Fly    67 GLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNID 131
            ||:|.:||||||.|.|||.::|||.:||||.|:.:|.|.:|.|:.|.|..|..|.:....|::.|
Zfish   104 GLSLNQKWNTDNVLTTEVTLEDQLTKGLKLGLDTSFVPNTGKKSAKLKTGYKREYMNVGCDLDFD 168

  Fly   132 LKGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQR 196
            |.||.::|:|||||:|||||||.||||.:|||..|||||||...||.|||.||||.||.|||:|:
Zfish   169 LAGPTVHAAAVLGYEGWLAGYQMAFDTAKSKLAQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQK 233

  Fly   197 TSDKLDVGVQLSWASGTSNTKFAIGAKYQLDDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTL 261
            .:.:|:..|.|:|.:|::||:|.|.||||||.|:||.|||||||.||:||.|.||.||.||||.|
Zfish   234 VNGQLETAVNLAWTAGSNNTRFGIAAKYQLDKDSSVSAKVNNASLVGVGYTQSLRPGVKLTLSAL 298

  Fly   262 VDGKNFNAGGHKIGVGLELE 281
            :|.|||||||||:|:|.|||
Zfish   299 IDAKNFNAGGHKVGMGFELE 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
porin	NP_001033899.1	Porin3_VDAC	3..281	CDD:132767	171/278 (62%)
vdac3	XP_005166800.1	Porin3_VDAC	39..318	CDD:132767	171/278 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	362	1.000	Domainoid score	I903
eggNOG	1	0.900	-	-		E1_KOG3126
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	372	1.000	Inparanoid score	I2074
OMA	1	1.010	-	-		QHG51941
OrthoDB	1	1.010	-	-		D550640at33208
OrthoFinder	1	1.000	-	-		FOG0001091
OrthoInspector	1	1.000	-	-		otm24409
orthoMCL	1	0.900	-	-		OOG6_101484
Panther	1	1.100	-	-	LDO	PTHR11743
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1638
SonicParanoid	1	1.000	-	-		X928
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870