DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment porin and SPAC1635.01

DIOPT Version :9

Sequence 1:	NP_001033899.1	Gene:	porin / 34500	FlyBaseID:	FBgn0004363	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_001342966.1	Gene:	SPAC1635.01 / 2542750	PomBaseID:	SPAC1635.01	Length:	282	Species:	Schizosaccharomyces pombe

Alignment Length:	286	Identity:	86/286 - (30%)
Similarity:	145/286 - (50%)	Gaps:	8/286 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAPPSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGIEFNTAGHSNQES-GKVFGSLETKYKVK 64
            ||||:|:.:.|...|:..:.:..|...|.::|...:|:.||.:|  ||:: |.:.|.|||.:..|
pombe     1 MAPPAYAAINKLCNDLLQRDFPVGATLLSVRTTAPNGVVFNVSG--NQDAKGVISGKLETSFNDK 63

  Fly    65 DYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVN 129
            ..|||:::.|.|.|.|.::|.:.:|...||.|::...|:|.:..|.....:.:.|..:...:.||
pombe    64 ANGLTISQGWTTANVLESKVGLSEQFAPGLHLNVNTTFSPATAAKTAILNLEHQHPLIHTHASVN 128

  Fly   130 IDLKGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDF-VLHTAVNDGQEFSGSI 193
            . |:...:....| |::|:|||.:..:|.|:..::.....:||..... |...|.|:...|..|.
pombe   129 A-LERKFLGDFTV-GHEGFLAGAEFGYDVQKGNVSNYAATIGYLASPLSVALQASNNLSVFRASY 191

  Fly   194 FQRTSDKLDVGVQLSW-ASGTSNT-KFAIGAKYQLDDDASVRAKVNNASQVGLGYQQKLRDGVTL 256
            :.|.|..::.|..::| |:.|:|. ...:.:||.||.|..|:.|:|:|....|.|.|.:|.|||:
pombe   192 YHRVSSDVEAGGNVTWDAASTANAITLELASKYALDKDTFVKGKINSAGVATLSYFQTVRPGVTV 256

  Fly   257 TLSTLVDGKNFNAGGHKIGVGLELEA 282
            .|...:|.:......||.|:.|...|
pombe   257 GLGLQLDTQRLGQPAHKAGLSLAFSA 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
porin	NP_001033899.1	Porin3_VDAC	3..281	CDD:132767	83/281 (30%)
SPAC1635.01	NP_001342966.1	Porin3_VDAC	3..281	CDD:132767	83/281 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	135	1.000	Domainoid score	I1267
eggNOG	1	0.900	-	-		E1_KOG3126
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37765
Inparanoid	1	1.050	140	1.000	Inparanoid score	I1372
OMA	1	1.010	-	-		QHG51941
OrthoFinder	1	1.000	-	-		FOG0001091
OrthoInspector	1	1.000	-	-		otm47247
orthoMCL	1	0.900	-	-		OOG6_101484
Panther	1	1.100	-	-	LDO	PTHR11743
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1638
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.860