DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment porin and Vdac3

DIOPT Version :9

Sequence 1:	NP_001033899.1	Gene:	porin / 34500	FlyBaseID:	FBgn0004363	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_001185927.1	Gene:	Vdac3 / 22335	MGIID:	106922	Length:	284	Species:	Mus musculus

Alignment Length:	280	Identity:	163/280 - (58%)
Similarity:	216/280 - (77%)	Gaps:	1/280 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGI-EFNTAGHSNQESGKVFGSLETKYKVKDYG 67
            |:|.||||.|:|:|:|||.||:.|:|||||:.||: ||:|:||:..::||..|:|||||||.:||
Mouse     5 PTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVMEFSTSGHAYTDTGKASGNLETKYKVCNYG 69

  Fly    68 LTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNIDL 132
            ||.|:||||||||.||::.:::|.|||||:|:..|.|.:|.|:||.|.:|..:.....|:|:||.
Mouse    70 LTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYRRDCFSLGSNVDIDF 134

  Fly   133 KGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRT 197
            .||.|...|||.::|||||||.:|||.:|||:.|||||||...||.|||.||||.||.|||:|:.
Mouse   135 SGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKV 199

  Fly   198 SDKLDVGVQLSWASGTSNTKFAIGAKYQLDDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLV 262
            :::::..:.|:|.:|::||:|.|.|||:||...|:.|||||||.:||||.|.||.||.||||.|:
Mouse   200 NERIETSINLAWTAGSNNTRFGIAAKYKLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALI 264

  Fly   263 DGKNFNAGGHKIGVGLELEA 282
            |||||||||||:|:|.||||
Mouse   265 DGKNFNAGGHKVGLGFELEA 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
porin	NP_001033899.1	Porin3_VDAC	3..281	CDD:132767	160/277 (58%)
Vdac3	NP_001185927.1	Porin3_VDAC	5..283	CDD:132767	160/277 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	353	1.000	Domainoid score	I996
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	362	1.000	Inparanoid score	I2175
Isobase	1	0.950	-	0	Normalized mean entropy	S1329
OMA	1	1.010	-	-		QHG51941
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001091
OrthoInspector	1	1.000	-	-		otm43617
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11743
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1638
SonicParanoid	1	1.000	-	-		X928
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.050