DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment porin and Vdac2

DIOPT Version :9

Sequence 1:	NP_001033899.1	Gene:	porin / 34500	FlyBaseID:	FBgn0004363	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_035825.1	Gene:	Vdac2 / 22334	MGIID:	106915	Length:	295	Species:	Mus musculus

Alignment Length:	280	Identity:	172/280 - (61%)
Similarity:	216/280 - (77%)	Gaps:	0/280 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PPSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYG 67
            ||.|:||||.|||||:||:.|||.|||:|||:.||:||:|:|.||.::|||.|:||||||..:||
Mouse    16 PPPYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYG 80

  Fly    68 LTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNIDL 132
            ||.||||||||||.||:|::||:.:||||:.:..|:|.:|.|:||.|.||..|.:....||:.|.
Mouse    81 LTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSAYKRECINLGCDVDFDF 145

  Fly   133 KGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRT 197
            .||.|:.|||.||:|||||||..||:.:||||.:|||:||.|.||.|||.||:|.||.|||:|:.
Mouse   146 AGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKV 210

  Fly   198 SDKLDVGVQLSWASGTSNTKFAIGAKYQLDDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLV 262
            .:..|..|.|:|.|||:.|:|.|.||||||..||:.|||||:|.:|:||.|.||.||.||||.||
Mouse   211 CEDFDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALV 275

  Fly   263 DGKNFNAGGHKIGVGLELEA 282
            |||:|||||||:|:.|||||
Mouse   276 DGKSFNAGGHKLGLALELEA 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
porin	NP_001033899.1	Porin3_VDAC	3..281	CDD:132767	169/277 (61%)
Vdac2	NP_035825.1	Porin3_VDAC	16..294	CDD:132767	169/277 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	353	1.000	Domainoid score	I996
eggNOG	1	0.900	-	-		E1_KOG3126
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37765
Inparanoid	1	1.050	362	1.000	Inparanoid score	I2175
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51941
OrthoDB	1	1.010	-	-		D550640at33208
OrthoFinder	1	1.000	-	-		FOG0001091
OrthoInspector	1	1.000	-	-		otm43617
orthoMCL	1	0.900	-	-		OOG6_101484
Panther	1	1.100	-	-	O	PTHR11743
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1638
SonicParanoid	1	1.000	-	-		X928
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.870