Protein Alignment Porin2 and VDAC1

DIOPT Version :10

• Sequence 1: NP_609462.1
• Gene: Porin2 / 34499
• FlyBaseID: FBgn0069354
• Length: 293
• Species: Drosophila melanogaster
• Sequence 2: NP_001387957.1
• Gene: VDAC1 / 7416
• HGNCID: 12669
• Length: 297
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 101/305 - (33%)
• Similarity: 167/305 - (54%)
• Gaps: 25/305 - (8%)

  Fly     3 AKTPTYPDLGKLARDLFKRGYHPGIWQIDCKTLTNSGIEFFTTGFASQDNSKVTGSLQSKYKIED 67
            |..|||.||||.|||:|.:||..|:.::|.||.:.:|:||.::|.|:.:.:||||||::||:..:
Human     2 AVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTE 66

  Fly    68 QGLTLTERWNTENWLFGEIMHRDKLAQGLMLAVEAKFQPGSN--------------EADGKFKMG 118
            .|||.||:|||:|.|..||...|:||:||.|..::.|.|.:.              :.:.|.|.|
Human    67 YGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGLSPCGREVVSCSLWKKNAKIKTG 131

  Fly   119 YAQDNFNFLADIGLN-SEPILNCSLVVGHKEFLGGVGTEFDVGNTELKGWKVALGWTNETATLHG 182
            |.:::.|...|:..: :.|.:..:||:|::.:|.|....|:...:.:.....|:|:..:...||.
Human   132 YKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHT 196

  Fly   183 ELKNGDTWLASLFYKASEKIDAGIEVTKGAGGGEAAEGEQQGGDVVVNLGMIYHLEEDALVRAKV 247
            .:.:|..:..|::.|.::|::..:.:...||......|          :...|.::.||...|||
Human   197 NVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFG----------IAAKYQIDPDACFSAKV 251

  Fly   248 NNLVELGLGYEQKLRDGITASISAVLDCNNFKDGNHRFGVGIALQ 292
            ||...:||||.|.|:.||..::||:||..|...|.|:.|:|:..|
Human   252 NNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQ 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Porin2	NP_609462.1	Porin3_VDAC	6..292	CDD:132767	99/300 (33%)
VDAC1	NP_001387957.1	Porin3_VDAC	4..296	CDD:132767	99/301 (33%)