Protein Alignment CG17139 and VDAC3

DIOPT Version :10

• Sequence 1: NP_001033898.1
• Gene: CG17139 / 34497
• FlyBaseID: FBgn0260454
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001129166.1
• Gene: VDAC3 / 7419
• HGNCID: 12674
• Length: 284
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 72/295 - (24%)
• Similarity: 116/295 - (39%)
• Gaps: 45/295 - (15%)

  Fly    62 PSYFHVGLLAKMCLIHGYTIGRWKL-----QCTSKTEKDFYLSSFGEGYPTWNTVYGGLEAYKES 121
            |:|..:|..||.....||..|..|:     .|:...|    .|:.|..|.......|.||...:.
Human     5 PTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVME----FSTSGHAYTDTGKASGNLETKYKV 65

  Fly   122 GNFHASLA--WLSDGDLLSDLGVH---GDGLGGTWSTVLKSMVSYPEGRKFQCKLKCGFDRNPGK 181
            .|:..:..  |.:|..|.:::...   .:||..|..|:.     .|...|...|||..:.|:...
Human    66 CNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIF-----VPNTGKKSGKLKASYKRDCFS 125

  Fly   182 VEMYIPI-YKEPLLMGYIMMQPVKNYLLGYRTVFNVEDRDFNMHAFCGGYS----------NDVT 235
            |...:.| :..|.:.|:.:: ..:.:|.||:..|:......:.:.|..||.          ||.|
Human   126 VGSNVDIDFSGPTIYGWAVL-AFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGT 189

  Fly   236 EVGLKFENFKALRGSIFQRIGEKWAVALKANLYGNVSAKSVSIG--GQYEWEPGSMLKAKVRGDS 298
            |.|          |||:|::.||  :....||.....:.:...|  .:|..:..:.|.|||...|
Human   190 EFG----------GSIYQKVNEK--IETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNAS 242

  Fly   299 RIGLIFQKKLREDIEVLFHVGFEGSDPINGKHKFG 333
            .|||.:.:.||..:::......:|.:...|.||.|
Human   243 LIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVG 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17139	NP_001033898.1	Porin3_VDAC	63..339	CDD:132767	71/294 (24%)
VDAC3	NP_001129166.1	Porin3_VDAC	5..283	CDD:132767	72/295 (24%)