Protein Alignment CG17139 and VDAC1

DIOPT Version :10

• Sequence 1: NP_001033898.1
• Gene: CG17139 / 34497
• FlyBaseID: FBgn0260454
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001387957.1
• Gene: VDAC1 / 7416
• HGNCID: 12669
• Length: 297
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 72/293 - (24%)
• Similarity: 115/293 - (39%)
• Gaps: 28/293 - (9%)

  Fly    62 PSYFHVGLLAKMCLIHGYTIGRWKLQCTSKTEKDFYLSSFGEGYPTWNTVYGGLEA---YKESGN 123
            |:|..:|..|:.....||..|..||...:|:|.....:|.|........|.|.||.   :.|.|
Human     5 PTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYG- 68

  Fly   124 FHASLAWLSDGDLLSDLGVHGD---GLGGTWSTVLKSMVSY-PEGR--------KFQCKLKCGFD 176
            ...:..|.:|..|.:::.|...   ||..|:.:........ |.||        |...|:|.|:.
Human    69 LTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGLSPCGREVVSCSLWKKNAKIKTGYK 133

  Fly   177 R---NPG---KVEMYIPIYKEPLLMGYIMMQPVKNYLLGYRTVFNVEDRDFNMHAFCGGYSNDVT 235
            |   |.|   ..::..|..:..|::||      :.:|.||:..|...........|..||..|..
Human   134 REHINLGCDMDFDIAGPSIRGALVLGY------EGWLAGYQMNFETAKSRVTQSNFAVGYKTDEF 192

  Fly   236 EVGLKFENFKALRGSIFQRIGEKWAVALKANLYGNVSAKSVSIGGQYEWEPGSMLKAKVRGDSRI 300
            ::.....:.....|||:|::.:|...|:........|.....|..:|:.:|.:...|||...|.|
Human   193 QLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLI 257

  Fly   301 GLIFQKKLREDIEVLFHVGFEGSDPINGKHKFG 333
            ||.:.:.|:..|::......:|.:...|.||.|
Human   258 GLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLG 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17139	NP_001033898.1	Porin3_VDAC	63..339	CDD:132767	71/292 (24%)
VDAC1	NP_001387957.1	Porin3_VDAC	4..296	CDD:132767	72/293 (25%)