Protein Alignment CG6700 and Leng8

DIOPT Version :9

• Sequence 1: NP_001162944.1
• Gene: CG6700 / 34496
• FlyBaseID: FBgn0032305
• Length: 874
• Species: Drosophila melanogaster
• Sequence 2: XP_036008825.1
• Gene: Leng8 / 232798
• MGIID: 2142195
• Length: 818
• Species: Mus musculus
• Alignment Length: 949
• Identity: 288/949 - (30%)
• Similarity: 392/949 - (41%)
• Gaps: 272/949 - (28%)

  Fly     2 SDAMSAPPPLIPQ------LQEMQQQQQQSANPAQLAQQWSNYAWYANQNAAYQQQYQQYYQYYV 60
            |.|.|:.|....|      ...:||||||            .|.||...|.||...|......|.
Mouse    58 SKASSSGPVASAQYVSQAEASALQQQQQQ------------YYQWYQQYNYAYPYSYYYPMSMYQ 110

  Fly    61 RYQQQQQQQVTSTV--------------STSNAP--PGFSNAL----------AAPPPLPS---- 95
            .|....|..:.|:.              .|.|.|  ||...::          ||.||.||
Mouse   111 SYGSPSQYGMASSYGSATAQQPSAPQHQGTLNQPPVPGMDESMAYQASPQQLPAAQPPQPSNSQH 175

  Fly    96 -------GPPPPPPP-----QIGQPPGQNKQQQQQQQQQQLQQQQQQQQQQQQQQQKNFGGIRFN 148
                   ||.|...|     |.|.|.||  ........:..:.::.||...:.:.....||::||
Mouse   176 GTHSLSNGPQPGTAPSTQHSQAGAPTGQ--AYGPHSYSEPAKPKKGQQLWTRMKPAPGTGGLKFN 238

  Fly   149 LNLNQKRLAGAPNPLQQQQQQQHQQQQHQQQQQVMQLYNNNNSNKKKRKRNNKNKNFEQSTYSNP 213
            :   |||    |..:..|....:.:.||
Mouse   239 I---QKR----PFAVTSQSFSSNSEGQH------------------------------------- 259

  Fly   214 FANQTPATPQAPPPPIISASDVGVPINPDLSKPPPPLPLAIVAPTENPQHQKQQQQEHMAAQRAG 278
                               |..|                        ||...:..|........|
Mouse   260 -------------------SSFG------------------------PQPNSENTQNRSGPSGRG 281

  Fly   279 EATSQTSNFKRPNSFQMASSDSWPNSLNQYVARCYSKCNTDLDKDQIDICLKGKIIAAANRNELW 343
            ..:.:              .|.||..:.:||.||::.|.::.|||:.:..||..:.|.......:
Mouse   282 NLSGK--------------PDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAY 332

  Fly   344 TRDWDNEPMP----------TVYSERDGIDVVLSNVPPPQQQRSNYFQKKQEQERERERDREADK 398
            |.||..||:|          |..:|..|    |:..|..:..:    :|:.|........|.|..
Mouse   333 TIDWSREPLPGQSWAWSLSCTTVAELPG----LTREPVAESPK----KKRWEAPSSLHPSRGAGS 389

  Fly   399 ------------SPAKGSTGIV--NQFKQKGNQ--FNKASSSYGSHHSSSSKYSRSRSRSPSSSN 447
                        :|..|..|..  :.|.:.||:  |.|.:||    .||:...|||.||||:
Mouse   390 VTRGGGAQSQRGTPGAGGAGRARGSSFTKFGNRNVFMKDNSS----SSSTDSRSRSSSRSPT--- 447

  Fly   448 SLKYSSKKRYSRSRSRSRSRSRSPRSRSCSRSSDASSPPARKIIRKSGSNESLNFIPLTANLSRK 512
                   :.:.||.|.|.|.| |.....|......:.||.    .:.|..         |::.|.
Mouse   448 -------RHFRRSDSHSDSDS-SYSGNECHPVGRRNPPPK----GRGGRG---------AHMDRG 491

  Fly   513 QQKMLMKKGKRAAAMASAQMKKKDTPHFYSNQSSVGGAVDDDTAR---LQQRAARFSQQGSSSAK 574
            :.:  .::|||.....:.:.:||           :.....:|..|   .|:||||| |.|.|...
Mouse   492 RGR--AQRGKRHDLAPTKRSRKK-----------MAALECEDPERELKKQKRAARF-QHGHSRRL 542

  Fly   575 KSVVAIASSPFGLTTAKNKKKMVQQHQQHQRSAFYEDTEAASGIDLLDLHIVGTCRDLEKSFLRL 639
            :                 .:.:|.|....:.|....|.:        :|.|||||.|:.|.:|||
Mouse   543 R-----------------LEPLVLQMSNLESSGADPDWQ--------ELQIVGTCPDITKHYLRL 582

  Fly   640 TKAPSPSEVRPVEVLTHSLVNVKGKWRANQDYHYACDQLKSIRQDLTVQGIRDQFTVEVYETHAR 704
            |.||.||.||||.||..||..||..|:..|||.:||:|:|||||||||||||.:|||||||||||
Mouse   583 TCAPDPSTVRPVAVLKKSLCMVKSHWKEKQDYAFACEQMKSIRQDLTVQGIRTEFTVEVYETHAR 647

  Fly   705 IAMEKGDHEEFNQCQTQLKMLYME-IGGKNANALEFTAYRILYYIFTKNTLDITTVMRSITADQR 768
            ||:||||||||||||||||.||.| :.|   |..|||||||||||||||:.||||.:..:|.:.:
Mouse   648 IALEKGDHEEFNQCQTQLKSLYAENLAG---NVGEFTAYRILYYIFTKNSGDITTELAYLTREMK 709

  Fly   769 ENPVIAHALQFRSAWSLGNYCKLFSLYRTAPLMSGHMIEWFLERERKAALRVIIKSYRPNISVDY 833
            .:|.:||||..|:||:||||.:.|.||..||.|||::::.|.:|||||||:.:||::||.:.|.|
Mouse   710 ADPCVAHALALRAAWALGNYHRFFRLYCHAPCMSGYLVDKFADRERKAALKAMIKTFRPALPVSY 774

  Fly   834 ITKILAFDSSEKCKEWLDTFSLPYAA-DGAQVDCKNAAA 871
            :...|||:....|:.:|:...|.|.. |.:.|||:.:.|
Mouse   775 LQAELAFEGEAACRAFLEPLGLSYTGPDNSSVDCRLSLA 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6700	NP_001162944.1	SAC3_GANP	643..840	CDD:281402	122/197 (62%)
Leng8	XP_036008825.1	PRK10263	<113..>399	CDD:236669	70/396 (18%)
		CSN8_PSD8_EIF3K	585..799	CDD:420155	128/216 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	239	1.000	Domainoid score	I2285
eggNOG	1	0.900	-	-		E1_KOG1861
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2573
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003794
OrthoInspector	1	1.000	-	-		oto95109
orthoMCL	1	0.900	-	-		OOG6_101802
Panther	1	1.100	-	-	LDO	PTHR12436
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1512
SonicParanoid	1	1.000	-	-		X3733
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.940