DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6700 and LOC100495696

DIOPT Version :9

Sequence 1:	NP_001162944.1	Gene:	CG6700 / 34496	FlyBaseID:	FBgn0032305	Length:	874	Species:	Drosophila melanogaster
Sequence 2:	XP_002938562.3	Gene:	LOC100495696 / 100495696	-ID:	-	Length:	795	Species:	Xenopus tropicalis

Alignment Length:	904	Identity:	291/904 - (32%)
Similarity:	420/904 - (46%)	Gaps:	175/904 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MSAPPPLIPQLQEMQQ--QQQQSANPAQLAQQWSNYAWYANQNAAYQQ-----QYQQYYQYYVRY 62
            |..|....|:.::.:|  .....||.|...:...|  ..||...|.||     |.|||||:|.:|
Frog    27 MDVPMQENPEWEKARQALASISKANAASTNKGSEN--GQANSQFASQQGDAALQQQQYYQWYSQY 89

  Fly    63 QQQQQQQVTSTVSTSNAPPGFSNALAAPPPLPSGPPPPPPPQIGQPPGQNKQQQQQQQQQQLQQQ 127
            ...........::..|   |: ||                      |||.......||.|...|.
Frog    90 NYSYPYNYYYQMNMYN---GY-NA----------------------PGQYGMAGNYQQSQSAGQH 128

  Fly   128 QQQQQQQQQQQQKNFGGIRFNLNLNQKRLAG------------APNPLQQQQQQQHQQQQHQQQQ 180
            |.                    ||.|..:.|            :|.|....|....|...|...:
Frog   129 QG--------------------NLTQPPVPGLEDSNMSYSNVQSPIPSSNNQSASRQHLNHTMAK 173

  Fly   181 QVMQLYNNNNSNKKKRKRNNKNKNFEQSTYSNPFANQTP----------ATPQAPPPPIISASDV 235
            ..:|..|..|.:.::...|       ||.|..|..|:.|          ...|||       ...
Frog   174 ACIQGGNPGNQSNQQHSSN-------QSNYCQPSFNEGPKPKKGQQLWNRMKQAP-------GSG 224

  Fly   236 GVPINPDLSKPPPPLPLAIVAPTENPQHQKQQQQE---HMAAQRAGEATSQTSNFKRPNSFQMAS 297
            |...|  :.|.|..:.....||:::..:...|||.   |.|.|:..:...:.......||   |.
Frog   225 GFKFN--IQKRPLVMANQNFAPSDHHGNSAAQQQAAHLHHALQQQQQPKLEKIAEHGSNS---AK 284

  Fly   298 SDSWPNSLNQYVARCYSKCNTDLDKDQIDICLKGKIIAAANRNELWTRDWDNEPMPTVYSERDGI 362
            .:.||.::.:||.||::.|.::.|||:.:..||..:.|.......:|.||..||:|       |.
Frog   285 PEDWPQAMKEYVQRCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLP-------GK 342

  Fly   363 DVVLSNVPPPQQQRSNYFQKKQEQERERERDREADKSPAKGSTGIVNQFKQKGNQFNKASSSYGS 427
            |.|                   ::..:::|..:|....::||:..:.|..:.|..    |:|.|:
Frog   343 DSV-------------------KESPKKKRWEQAALQSSRGSSITITQSPRGGIN----STSAGT 384

  Fly   428 HHSSSSKYSRSRSRSPSSSNSLKYSSKKRYSRSRSRSRSRSRSPRSRSCSRSSDASSPPARKIIR 492
            .....|..::..:|:.    .:|.||....:.|||||||.|.||..|.....||:.|..:...||
Frog   385 LRGRGSFITKFGNRNV----FMKESSTSSSAGSRSRSRSSSHSPHRRYRRSGSDSDSSFSGNEIR 445

  Fly   493 KSGSNESLNFIPLTANLSRKQQKMLMKKGKRAAAMASAQMKKKDTPHFYSNQSSVGGAVDDDTA- 556
            :.|............::.|.:.:  |::|||:....:.:.:||:|         |...::|...
Frog   446 EGGRKNFQKGRGRGGHMDRGRGR--MQRGKRSDQAFNKKNRKKNT---------VTMELEDPEKE 499

  Fly   557 -RLQQRAARFSQQGSSSAKKSVVAIASSPFGLTTAKNKKKMVQQHQQHQRSAFYEDTEAASGIDL 620
             :.::||||| |.|....|     :...|.          ::|.:..        |..|:..:|.
Frog   500 FKKEKRAARF-QHGHGPKK-----LRMEPL----------VLQINNM--------DHSASENLDW 540

  Fly   621 LDLHIVGTCRDLEKSFLRLTKAPSPSEVRPVEVLTHSLVNVKGKWRANQDYHYACDQLKSIRQDL 685
            .::.||||.:|:.|::||||.||.||.||||.||..|||.||..::..|||.:||:|:|||||||
Frog   541 NEIKIVGTSQDITKNYLRLTCAPDPSTVRPVPVLKKSLVMVKADFKNKQDYAFACEQMKSIRQDL 605

  Fly   686 TVQGIRDQFTVEVYETHARIAMEKGDHEEFNQCQTQLKMLYME-IGGKNANALEFTAYRILYYIF 749
            ||||||.:|||||||||||||:||||||||||||.|||.||.| :.|   |..||||||||||||
Frog   606 TVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQAQLKALYAENLAG---NVGEFTAYRILYYIF 667

  Fly   750 TKNTLDITTVMRSITADQRENPVIAHALQFRSAWSLGNYCKLFSLYRTAPLMSGHMIEWFLERER 814
            |||:.|:||.:..:|.:.:.:..:||||..|.||:|.||.:.|.|||.:|.|||::|:.|.||||
Frog   668 TKNSGDLTTELAHLTKELKADACVAHALSLREAWALSNYHRFFKLYRESPRMSGYLIDKFAERER 732

  Fly   815 KAALRVIIKSYRPNISVDYITKILAFDSSEKCKEWLDTFSLPYAA-DGAQVDCKNAAAI 872
            ||||:.:||::||::.|.||...|||.:.|:|:.:|.:.||.:|. |.:::|||.:.|:
Frog   733 KAALKAMIKTFRPDLPVSYIQSELAFANEEECQSFLASLSLVFAGNDASKIDCKLSLAV 791

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6700	NP_001162944.1	SAC3_GANP	643..840	CDD:281402	121/197 (61%)
LOC100495696	XP_002938562.3	CSN8_PSD8_EIF3K	562..775	CDD:420155	129/215 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	257	1.000	Domainoid score	I1990
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1503267at2759
OrthoFinder	1	1.000	-	-		FOG0003794
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12436
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1512
SonicParanoid	1	1.000	-	-		X3733
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.140