Protein Alignment Nos and NCP1

DIOPT Version :10

• Sequence 1: NP_523541.2
• Gene: Nos / 34495
• FlyBaseID: FBgn0011676
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: NP_011908.1
• Gene: NCP1 / 856438
• SGDID: S000001084
• Length: 691
• Species: Saccharomyces cerevisiae
• Alignment Length: 753
• Identity: 179/753 - (23%)
• Similarity: 295/753 - (39%)
• Gaps: 185/753 - (24%)

  Fly   648 KQIARAVKFTSKLFGRALSKRIKATVLYATETGKSEQYAKQLCELLGHAFNAQIYC--MSDYDIS 710
            :.||:.|...:|.:          .||||::||.:|.|||:..:.|...||..:.|  :.:||..
Yeast    48 RDIAQVVTENNKNY----------LVLYASQTGTAEDYAKKFSKELVAKFNLNVMCADVENYDFE 102

  Fly   711 SIEHEALLI-VVASTFGNGDPPENGELFSQELYAMRVQESSEHGLQDSSIGSSKSFMKASSRQEF 774
            |:....::: :..||:|.||.|:....|
Yeast   103 SLNDVPVIVSIFISTYGEGDFPDGAVNF------------------------------------- 130

  Fly   775 MKLPLQQVKRIDRWDSLRGSTSDTFTEETFGPLSNVRFAVFALGSSAYPNFCAFGQYVDNILGEL 839
                                 .|.......|.|||:|:.:|.||:|.|..|....:..:..|...
Yeast   131 ---------------------EDFICNAEAGALSNLRYNMFGLGNSTYEFFNGAAKKAEKHLSAA 174

  Fly   840 GGERLLRVAYGDEMCG-QEQSFRKWAPEVFKLACETFCLDPEESLSDASLALQNDSLTVNTVRLV 903
            |..||.::...|:..| .::.:..|...:.::..:...||.:|    |....|.....:|.:
Yeast   175 GAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELHLDEQE----AKFTSQFQYTVLNEI--- 232

  Fly   904 PSANKGSLDSSLSKYHNKKVHCCKAKAKPHNLTRLSEG----------------AKTTML----- 947
              .:..||....:.|           ...|.|.|.::|                .|:..|
Yeast   233 --TDSMSLGEPSAHY-----------LPSHQLNRNADGIQLGPFDLSQPYIAPIVKSRELFSSND 284

  Fly   948 -------LEICAPGLEYEPGDHVGIFPANRTELVDGLLNRLVGVDNPDEVLQLQLLKEKQTSNGI 1005
                   .::....::|..|||:.::|:|..|.|:..|: :..:| |:.:..|:.|
Yeast   285 RNCIHSEFDLSGSNIKYSTGDHLAVWPSNPLEKVEQFLS-IFNLD-PETIFDLKPL--------- 338

  Fly  1006 FKCWEPHDKIP---PDTLRNLLARFFDLTTPPSRQLLTLLAGFCEDTADKERLELLVNDSSAYE- 1066
                :|..|:|   |.|:...:..:.::|.|.||||.:.|..|..:...||:|.||..|...:.
Yeast   339 ----DPTVKVPFPTPTTIGAAIKHYLEITGPVSRQLFSSLIQFAPNADVKEKLTLLSKDKDQFAV 399

  Fly  1067 --DWRHWRLPHLLDVLEEFPSC-RPPAPLLLAQLTPLQPRFYSISSSPRRVSDEIHLTVAIVKY- 1127
              ..:::.:...|..|.:.... ..|...|:..:..:.||:||||||.......:|:|..:..:
Yeast   400 EITSKYFNIADALKYLSDGAKWDTVPMQFLVESVPQMTPRYYSISSSSLSEKQTVHVTSIVENFP 464

  Fly  1128 RCEDGQGDERYGVCSNYLSGLR--------------------------ADDELFMFVRSALGFHL 1166
            ..|........||.:|.|..::                          |:.:|.:.||.: .|.|
Yeast   465 NPELPDAPPVVGVTTNLLRNIQLAQNNVNIAETNLPVHYDLNGPRKLFANYKLPVHVRRS-NFRL 528

  Fly  1167 PSDRSRPIILIGPGTGIAPFRSFWQEFQVLSDLDPTAK------LPKMWLFFGCRNRDVDLYAEE 1225
            ||:.|.|:|:||||||:||||.|.:|  .::.|:...|      |.|..||:|.||.|..||.:|
Yeast   529 PSNPSTPVIMIGPGTGVAPFRGFIRE--RVAFLESQKKGGNNVSLGKHILFYGSRNTDDFLYQDE 591

  Fly  1226 KAELQKDQILDRVF---LALSREQAIPKTYVQDLIEQEFDSLYQLIVQERGHIYVCGDVT-MAEH 1286
            ..|..|.  ||..|   :|.||.....|.||||.::...|.::::| .....||||||.. ||:.
Yeast   592 WPEYAKK--LDGSFEMVVAHSRLPNTKKVYVQDKLKDYEDQVFEMI-NNGAFIYVCGDAKGMAKG 653

  Fly  1287 VYQTIRKCIAGKEQKSEAEVETFLLTLRDESRYHEDIF 1324
            |...:...::..:..:..|....:..|:...||.||::
Yeast   654 VSTALVGILSRGKSITTDEATELIKMLKTSGRYQEDVW 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nos	NP_523541.2	NOS_oxygenase_euk	216..624	CDD:238410
		Flavodoxin_1	673..863	CDD:425562	42/193 (22%)
		Nitric_oxide_synthase	931..1328	CDD:99799	123/466 (26%)
NCP1	NP_011908.1	Flavodoxin_1	63..199	CDD:425562	42/193 (22%)
		CYPOR	264..691	CDD:99801	119/447 (27%)