Protein Alignment Nos and TAH18

DIOPT Version :10

• Sequence 1: NP_523541.2
• Gene: Nos / 34495
• FlyBaseID: FBgn0011676
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: NP_015373.1
• Gene: TAH18 / 856161
• SGDID: S000006252
• Length: 623
• Species: Saccharomyces cerevisiae
• Alignment Length: 682
• Identity: 162/682 - (23%)
• Similarity: 263/682 - (38%)
• Gaps: 173/682 - (25%)

  Fly   665 LSKRIKATVLYATETGKSEQYAKQLCELLGHAFNAQIYC-MSDYDISSIEHEALLIVVASTFGNG 728
            :|...|..:||.:|||.:..:|..|...|.....:..:| :.|||...|.....|.::.||.|.|
Yeast     1 MSSSKKIVILYGSETGNAHDFATILSHRLHRWHFSHTFCSIGDYDPQDILKCRYLFIICSTTGQG 65

  Fly   729 DPPENGELFSQELYAMRVQESSEHGLQDSSIGSSKSFMKASSRQEFMKLPLQQVKRIDRWDSLRG 793
            :.|.|                 .:.|:.....:..||:|..:      ||...
Yeast    66 ELPRN-----------------VNALKGERPVTFWSFLKRKN------LPSNL------------ 95

  Fly   794 STSDTFTEETFGPLSNVRFAVFALGSSAYPNFCAFG--QYVDNILGELGGERLLRVAYGDEMC-- 854
                         |::::.|:..||.|:||.| .:|  :....|:.:||...|......|:..
Yeast    96 -------------LNHIQTAMLGLGDSSYPKF-NYGIRKLHQRIVTQLGANELFDRLEADDQAMA 146

  Fly   855 --------GQEQSFRKWAPEVFKLACETFC-------------LDPEESLSDASLALQND----- 893
                    |.|..:.::..:|.......:.             ||||..|..||....:|
Yeast   147 GSNKGTGLGIESVYFEYEKKVLSFLLSKYPNRKVNGQIIKREELDPEVYLEPASYLQLSDEHANE 211

  Fly   894 -------------SLTVNTVRLVPSANKGSLDSSLSKYHNKKVHCCKAKAKPHNLTRLSEGAKTT 945
                         ||.|..|.:    ||    ...|:.|.:.|.    :.|..|:.::.|
Yeast   212 KFTSTKVIFEGDESLKVGRVNI----NK----RITSEGHFQDVR----QFKFSNVDKIQE----- 259

  Fly   946 MLLEICAPGLEYEPGDHVGIFPANRTELVDGLL-NRLVGVDNPDEVLQLQLLKEKQTSNGIFKCW 1009
                      .|||||.|.|:|.|..|.|...| |:...::..|:.|..        ::|:
Yeast   260 ----------NYEPGDTVTIYPCNTDEDVSRFLANQSHWLEIADKPLNF--------TSGV---- 302

  Fly  1010 EPHD-----KIPPDTLRNLLARFFDLTTPPSRQLLTLLAGFCEDTA-----------DKERLELL 1058
             |:|     .:.|.||||||....|..:.|.......:..|..|..           .:|:|...
Yeast   303 -PNDLKDGGLVRPMTLRNLLKYHCDFMSIPRTSFFLKIWTFATDVTKMERGQEQLNDQREKLRQF 366

  Fly  1059 VNDSSAYEDWRHWRLPH--LLDVLEEFPSCRPPAPLLLAQLTPLQPRFYSISSSPRRVSDEIHLT 1121
            ..|....:.:.:...|.  :|:|||:|.|.:.|...:|..|..::||:|||||.|.  ...|.||
Yeast   367 ATDQDMQDLYDYCNRPRRSILEVLEDFISVKLPWKYVLDYLPIIKPRYYSISSGPG--DPNIELT 429

  Fly  1122 VAIVKYRCEDGQGDERYGVCSNYLSGLRADDELFMFVRSALGFHLPSDR--SRPIILIGPGTGIA 1184
            ||||||:..  ....|.|:|:||::.|:..:::...:::.   |:....  ::|:||:|||.|:|
Yeast   430 VAIVKYKTI--LRKIRRGICTNYIARLQEGEQIRYKLQNN---HIIKKEFLNKPMILVGPGVGLA 489

  Fly  1185 PFRSFWQEFQVLSDLDPTAKLPKMWLFFGCRNRDVDLYAEEKAE--LQKDQILDRVFLALSREQA 1247
            |..|.     |.:::....|     |.||||.:|.|...::..|  .:|.:|......:...|.:
Yeast   490 PLLSV-----VKAEISKDIK-----LLFGCRYKDKDYIYKDMLEDWFRKGKIALHSSFSRDEENS 544

  Fly  1248 IPKTYVQDLIEQEFDSLYQLIVQERGHIYVCG 1279
            ....||||.:.:..:.:..|:|.:....::||
Yeast   545 PGVKYVQDYLWRLGEEITNLVVNKDAVFFLCG 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nos	NP_523541.2	NOS_oxygenase_euk	216..624	CDD:238410
		Flavodoxin_1	673..863	CDD:425562	42/202 (21%)
		Nitric_oxide_synthase	931..1328	CDD:99799	100/372 (27%)
TAH18	NP_015373.1	Flavodoxin_1	9..143	CDD:425562	40/182 (22%)
		FNR_like	230..623	CDD:447143	106/404 (26%)