DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nos and ATR2

DIOPT Version :9

Sequence 1:	NP_523541.2	Gene:	Nos / 34495	FlyBaseID:	FBgn0011676	Length:	1349	Species:	Drosophila melanogaster
Sequence 2:	NP_001328167.1	Gene:	ATR2 / 829144	AraportID:	AT4G30210	Length:	774	Species:	Arabidopsis thaliana

Alignment Length:	733	Identity:	213/733 - (29%)
Similarity:	320/733 - (43%)	Gaps:	128/733 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   628 VWKK-GRGESKGKKPRRKFNFKQIARAVKFTSKLFGRALSKRIKATVLYATETGKSEQYAKQLCE 691
            ||:: |.|.||..:|.:....|.....:.          ..|.|.|:.:.|:||.:|.:||.|.|
plant   134 VWRRSGSGNSKRVEPLKPLVIKPREEEID----------DGRKKVTIFFGTQTGTAEGFAKALGE 188

  Fly   692 LLGHAFNA---QIYCMSDYDISSIEHEALL------IVVASTFGNGDPPENGELFSQELYAMRVQ 747
            .....:..   :|..:.||.....|:|..|      ....:|:|:|:|.:|...|
plant   189 EAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARF---------- 243

  Fly   748 ESSEHGLQDSSIGSSKSFMKASSRQEFMKLPLQQVKRIDRWDSLRGSTSDTFTEETFGPLSNVRF 812
                          .|.|.:.:.|.|::|                                |:::
plant   244 --------------YKWFTEGNDRGEWLK--------------------------------NLKY 262

  Fly   813 AVFALGSSAYPNFCAFGQYVDNILGELGGERLLRVAYGDEMCGQEQSFRKWA----PEVFKLACE 873
            .||.||:..|.:|....:.||:||.|.|.:||::|..||:....|..|..|.    ||:..:..|
plant   263 GVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILRE 327

  Fly   874 -----------TFCLDPEESLSDASLALQNDSLTVNTVRLVPSANKGSLDSSLSKYHNKKVHCCK 927
                       ...|:...|:.|:..|..||         :..|| |:..:.....|..|.:..
plant   328 EGDTAVATPYTAAVLEYRVSIHDSEDAKFND---------INMAN-GNGYTVFDAQHPYKANVA- 381

  Fly   928 AKAKPHNLTRLSEGAKTTMLLEICAPGLEYEPGDHVGIFPANRTELVDGLLNRLVGVDNPDEVLQ 992
            .|.:.|  |..|:.:...:..:|...||.||.|||||:...|.:|.||..| ||:.: :||....
plant   382 VKRELH--TPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEAL-RLLDM-SPDTYFS 442

  Fly   993 LQLLKEKQTSNGIFKCWEPHDKIPPDTLRNLLARFFDLTTPPSRQLLTLLAGFCEDTADKERLEL 1057
            |.  .||:....|.....|  ..||..||..|.|:..|.:.|.:..|..||....|..:.|||:.
plant   443 LH--AEKEDGTPISSSLPP--PFPPCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKH 503

  Fly  1058 LVNDS--SAYEDWRHWRLPHLLDVLEEFPSCRPPAPLLLAQLTP-LQPRFYSISSSPRRVSDEIH 1119
            |.:.:  ..|..|.......||:|:.||||.:||..:..|.:.| ||||||||||||:.....||
plant   504 LASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIH 568

  Fly  1120 LTVAIVKYRCEDGQGDERYGVCSNYLSGL----RADD--ELFMFVRSALGFHLPSDRSRPIILIG 1178
            :|.|:|..:...|:..:  ||||.::...    ::::  ...:|||.: .|.||||...|||:||
plant   569 VTCALVYEKMPTGRIHK--GVCSTWMKNAVPYEKSENCSSAPIFVRQS-NFKLPSDSKVPIIMIG 630

  Fly  1179 PGTGIAPFRSFWQEFQVLSDLDPTAKLPKMWLFFGCRNRDVD-LYAEEKAELQKDQILDRVFLAL 1242
            ||||:||||.|.||...|  ::...:|....||||||||.:| :|.||.....:...|..:.:|.
plant   631 PGTGLAPFRGFLQERLAL--VESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAF 693

  Fly  1243 SREQAIPKTYVQDLIEQEFDSLYQLIVQERGHIYVCGDVT-MAEHVYQTIRKCIAGKEQKSEAEV 1306
            ||| ...|.|||..:..:...::.:|.| ..::|||||.. ||..|::::......:......:.
plant   694 SRE-GPTKEYVQHKMMDKASDIWNMISQ-GAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKA 756

  Fly  1307 ETFLLTLRDESRYHEDIF 1324
            |.|:..|:...||..|::
plant   757 EGFVKNLQTSGRYLRDVW 774

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nos	NP_523541.2	NOS_oxygenase_euk	216..624	CDD:238410
		CysJ	669..1323	CDD:223446	203/688 (30%)
		Flavodoxin_1	673..863	CDD:278677	45/198 (23%)
		Nitric_oxide_synthase	931..1328	CDD:99799	141/405 (35%)
ATR2	NP_001328167.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19384
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010