Protein Alignment Nos and tah18

DIOPT Version :10

• Sequence 1: NP_523541.2
• Gene: Nos / 34495
• FlyBaseID: FBgn0011676
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: NP_593046.2
• Gene: tah18 / 2542966
• PomBaseID: SPAC1296.06
• Length: 584
• Species: Schizosaccharomyces pombe
• Alignment Length: 701
• Identity: 157/701 - (22%)
• Similarity: 284/701 - (40%)
• Gaps: 177/701 - (25%)

  Fly   673 VLYATETGKSEQYAKQLCELLGH-AFNAQIYCMSDYDISSIEHEALLIVVASTFGNGDPPENGEL 736
            :||.:|||.:|..|:.|...|.. .::..:..|.|:::.::......:.:.||.|.|:.|.|...
pombe     8 ILYGSETGTAEGLAESLFRSLTRMGYDVLVNSMDDFNLENLLRPLQCVFICSTTGQGEMPLNMRK 72

  Fly   737 FSQELYAMRVQESSEHGLQDSSIGSSKSFMKASSRQEFMKLPLQQVKRIDRWDSLRGSTSDTFTE 801
            |.:.|                                                 ||....:||
pombe    73 FWRFL-------------------------------------------------LRKKLPNTF-- 86

  Fly   802 ETFGPLSNVRFAVFALGSSAYPNFCAFGQYVDNILGELGGERLLRVAYGDEM--CGQEQSFRKWA 864
                 |:::::|||..|.::|..|....:.:|:.|.:||.:.......|||.  .|.|..|..|.
pombe    87 -----LNDMQYAVFGCGDTSYTRFNWASKKLDSRLRQLGAQSFSSRGEGDEQHPDGVEGVFAYWC 146

  Fly   865 PEV-----------------FKLACETFCLDPEESLSDASLALQNDSLTVNTVRLVPSANKGSLD 912
            ..:                 |.|...:|.:..:|||.......:::    |.||    .::|.::
pombe   147 NHLYSQLAAIKTPSRPAFGEFDLLPPSFQIIIDESLGCKVKGFEDN----NIVR----HSRGKIE 203

  Fly   913 SSLSKYHNKKVHCCKAKAKPHNLTRLSEGAKTTMLLEICAPGLE-YEPGDHVGIFPANRTELVDG 976
            ::|  .|||::...|......:|.             ...|..| ::|||...::|.|
pombe   204 ATL--VHNKRISNIKHWQDVRHLA-------------FKIPNFERWKPGDVAVLYPWN------- 246

  Fly   977 LLNRLVGVDNPDEVLQLQLLKEKQTSNGIFKC--WE-------------PHDKIP--PDTLR--N 1022
                                 :..:.|...:|  ||             ...|:|  |:.|.  |
pombe   247 ---------------------DDMSVNSFIECMGWESIKYSPLIISSNVAERKLPWFPNILNVFN 290

  Fly  1023 LLARFFDLTTPPSRQLLTLLAGFCEDTADKERLELLVNDSSAYED----WRHWRLPH--LLDVLE 1081
            |:.....:.:.|||....:.:.|..:...||||:    :.|:|::    :.:...|.  :|:.|:
pombe   291 LVKYVLSIHSVPSRTFFEMASHFSNNKMHKERLQ----EFSSYKNIDDYYDYTTRPRRTVLETLQ 351

  Fly  1082 EFPSCRPPAPLLLAQLTPLQPRFYSISSSPRRVSDEIHLTVAIVKYRCEDGQGDERYGVCSNYLS 1146
            ||.|.:.|....|.....::.|.|||::.....:..:.|.||:|||  :......|.|:||.::.
pombe   352 EFKSVQIPIEYALDAFPVIRGRQYSIANRCDNSTGILELAVALVKY--QTILKSPRQGICSRWIC 414

  Fly  1147 GLRADDELFMFVRSALGF-HLPSDRSRPIILIGPGTGIAPFRSFWQEFQVLSDLDPTAKLPKMWL 1210
            .|..:....:.:..  || :|....::|:|::|||||:||.|:..|| ::.:.|....      |
pombe   415 DLHENTSFNIDILP--GFLNLSYQSNKPLIMVGPGTGVAPLRALIQE-RIYNGLKENL------L 470

  Fly  1211 FFGCRNRDVDLYAEEKAELQKDQILDRVFLALSREQAIPKTYVQDLIEQEFDSLYQLIVQERGHI 1275
            ||||||:.:|...|:..|...::...::|.|.||:|. .|.|||..|::..:.:|.|:.::.|..
pombe   471 FFGCRNKSMDFLFEKDWEKYTEEGTLKLFCAFSRDQE-KKKYVQHSIQENGELVYNLLNEKDGMF 534

  Fly  1276 YVCGDVTMAEHVYQTIRKCIAGKEQK----SEAEVETFLLTLRDESRYHED 1322
            :|.|.   :..:..:::..|||...|    |.::..:|:.:|..::||:::
pombe   535 FVSGS---SGKMPSSVKDAIAGIVSKYSGCSISDGYSFVTSLEKKNRYYQE 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nos	NP_523541.2	NOS_oxygenase_euk	216..624	CDD:238410
		Flavodoxin_1	673..863	CDD:425562	40/192 (21%)
		Nitric_oxide_synthase	931..1328	CDD:99799	101/423 (24%)
tah18	NP_593046.2	CysJ	5..579	CDD:440138	155/696 (22%)