| Sequence 1: | NP_523541.2 | Gene: | Nos / 34495 | FlyBaseID: | FBgn0011676 | Length: | 1349 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_032739.3 | Gene: | Nos3 / 18127 | MGIID: | 97362 | Length: | 1202 | Species: | Mus musculus |
| Alignment Length: | 1227 | Identity: | 556/1227 - (45%) |
|---|---|---|---|
| Similarity: | 755/1227 - (61%) | Gaps: | 97/1227 - (7%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 152 GVGVGQGAG-CPPSGSCTASGKSSRELSPSPKNQQQPRKMSQDYRSRAGSFMHLDDEGRSLLMRK 215
Fly 216 P-----MRLKNIEGRPEVYDTLHCKGREILSCSKATCTSSIMNIGNAAVEARK-----------S 264
Fly 265 DLILEHAKDFLEQYFTSIKRTSSTAHETRWKQVRQSIETTGHYQLTETELIYGAKLAWRNSSRCI 329
Fly 330 GRIQWSKLQVFDCRYVTTTSGMFEAICNHIKYATNKGNLRSAITIFPQRTDAKHDYRIWNNQLIS 394
Fly 395 YAGYKQADGKIIGDPMNVEFTEVCTKLGWKSKGSEWDILPLVVSANGHDPDYFDYPPELILEVPL 459
Fly 460 THPKFEWFSDLGLRWYALPAVSSMLFDVGGIQFTATTFSGWYMSTEIGSRNLCDTNRRNMLETVA 524
Fly 525 LKMQLDTRTPTSLWKDKAVVEMNIAVLHSYQSRNVTIVDHHTASESFMKHFENESKLRNGCPADW 589
Fly 590 IWIVPPLSGSITPVFHQEMALYYLKPSFEYQDPAWRTHVWKKGRGESKGKKPRRKFNFKQIARAV 654
Fly 655 KFTSKLFGRALSKRIKATVLYATETGKSEQYAKQLCELLGHAFNAQIYCMSDYDISSIEHEALLI 719
Fly 720 VVASTFGNGDPPENGELFSQELYAM--------RVQESSEHGLQDSSIGSSKSFMKASSRQEFMK 776
Fly 777 LPLQQVKRIDRWDSLRGSTSDTFTEETFGPLSNVRFAVFALGSSAYPNFCAFGQYVDNILGELGG 841
Fly 842 ERLLRVAYGDEMCGQEQSFRKWAPEVFKLACETFCLDPEESLSDASLALQNDSLTVNTVRLVPSA 906
Fly 907 NKGSLDSSLSKYHNKKVHCCKAKAKPHNLTRLSEGAKTTMLLEICA---PGLEYEPGDHVGIFPA 968
Fly 969 NRTELVDGLLNRLVGVDNPDEVLQLQLLKEKQTSNGIFKCWEPHDKIPPDTLRNLLARFFDLTTP 1033
Fly 1034 PSRQLLTLLAGFCEDTADKERLELLVNDSSAYEDWRHWRLPHLLDVLEEFPSCRPPAPLLLAQLT 1098
Fly 1099 PLQPRFYSISSSPRRVSDEIHLTVAIVKYRCEDGQGDERYGVCSNYLSGLRADDELFMFVRSALG 1163
Fly 1164 FHLPSDRSRPIILIGPGTGIAPFRSFWQEFQVLSDLDPTAKLP-KMWLFFGCRNRDVD-LYAEEK 1226
Fly 1227 AELQKDQILDRVFLALSREQAIPKTYVQDLIEQEFDS-LYQLIVQERGHIYVCGDVTMAEHVYQT 1290
Fly 1291 IRKCIAGKEQKSEAEVETFLLTLRDESRYHEDIFGITLRTAEIHTKSRATARIRMAS 1347 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Nos | NP_523541.2 | NOS_oxygenase_euk | 216..624 | CDD:238410 | 238/423 (56%) |
| CysJ | 669..1323 | CDD:223446 | 273/667 (41%) | ||
| Flavodoxin_1 | 673..863 | CDD:278677 | 85/197 (43%) | ||
| Nitric_oxide_synthase | 931..1328 | CDD:99799 | 171/402 (43%) | ||
| Nos3 | NP_032739.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..70 | 15/72 (21%) | |
| NOS_oxygenase_euk | 67..479 | CDD:238410 | 237/418 (57%) | ||
| Interaction with NOSIP. /evidence=ECO:0000250 | 97..485 | 231/401 (58%) | |||
| Calmodulin-binding. /evidence=ECO:0000255 | 490..509 | 8/18 (44%) | |||
| CysJ | 511..1158 | CDD:223446 | 275/673 (41%) | ||
| Flavodoxin_1 | 521..697 | CDD:278677 | 85/197 (43%) | ||
| FNR_like | 761..1163 | CDD:297884 | 171/404 (42%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 817..843 | 5/26 (19%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 526 | 1.000 | Domainoid score | I296 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 1113 | 1.000 | Inparanoid score | I226 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG46820 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0001418 | |
| OrthoInspector | 1 | 1.000 | - | - | otm44105 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_103176 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR19384 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4692 |
| SonicParanoid | 1 | 1.000 | - | - | X3122 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 12.000 | |||||