| Sequence 1: | NP_523541.2 | Gene: | Nos / 34495 | FlyBaseID: | FBgn0011676 | Length: | 1349 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_035057.1 | Gene: | Nos2 / 18126 | MGIID: | 97361 | Length: | 1144 | Species: | Mus musculus |
| Alignment Length: | 1119 | Identity: | 508/1119 - (45%) |
|---|---|---|---|
| Similarity: | 682/1119 - (60%) | Gaps: | 84/1119 - (7%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 217 MRLKNIEGRPEVYDTLHCKGREILSCSKATCTSSIMNIGNAAVEARKS----DLILEHAKDFLEQ 277
Fly 278 YFTSIKRTSSTAHETRWKQVRQSIETTGHYQLTETELIYGAKLAWRNSSRCIGRIQWSKLQVFDC 342
Fly 343 RYVTTTSGMFEAICNHIKYATNKGNLRSAITIFPQRTDAKHDYRIWNNQLISYAGYKQADGKIIG 407
Fly 408 DPMNVEFTEVCTKLGWKSKGSEWDILPLVVSANGHDPDYFDYPPELILEVPLTHPKFEWFSDLGL 472
Fly 473 RWYALPAVSSMLFDVGGIQFTATTFSGWYMSTEIGSRNLCDTNRRNMLETVALKMQLDTRTPTSL 537
Fly 538 WKDKAVVEMNIAVLHSYQSRNVTIVDHHTASESFMKHFENESKLRNGCPADWIWIVPPLSGSITP 602
Fly 603 VFHQEMALYYLKPSFEYQDPAWRTHVWKKGRGESKGKKPRRKFNFKQIARAVKFTSKLFGRALSK 667
Fly 668 RIKATVLYATETGKSEQYAKQLCELLGHAFNAQIYCMSDYDISSIEHEALLIVVASTFGNGDPPE 732
Fly 733 NGELFSQELYAMRVQESSEHGLQDSSIGSSKSFMKASSRQEFMKLPLQQVKRIDRWDSLRGSTSD 797
Fly 798 TFTEETFGPLSNVRFAVFALGSSAYPNFCAFGQYVDNILGELGGERLLRVAYGDEMCGQEQSFRK 862
Fly 863 WAPEVFKLACETFCLDPEESLSDASLALQNDSLTVNTVRLVPSANKGSLDSSLSKYHNKKVHCCK 927
Fly 928 AKAKPHNLTRLSEGAKTTMLLEIC---APGLEYEPGDHVGIFPANRTELVDGLLNRLVGVDNPDE 989
Fly 990 VLQLQLLKEKQTSNGIFKCWEPHDKIPPDTLRNLLARFFDLTTPPSRQLLTLLAGFCEDTADKER 1054
Fly 1055 LELLVNDSSAYEDWRHWRLPHLLDVLEEFPSCRPPAPLLLAQLTPLQPRFYSISSSPRRVSDEIH 1119
Fly 1120 LTVAIVKYRCEDGQGDERYGVCSNYLSGLRADDELFMFVRSALGFHLPSDRSRPIILIGPGTGIA 1184
Fly 1185 PFRSFWQEFQVLSDLDPTA-KLPKMWLFFGCRNRDVD-LYAEEKAELQKDQILDRVFLALSREQA 1247
Fly 1248 IPKTYVQDLIEQEF-DSLYQLIVQERGHIYVCGDVTMAEHVYQTIRKCIAGKEQKSEAEVETFLL 1311
Fly 1312 TLRDESRYHEDIFG 1325 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Nos | NP_523541.2 | NOS_oxygenase_euk | 216..624 | CDD:238410 | 230/410 (56%) |
| CysJ | 669..1323 | CDD:223446 | 261/659 (40%) | ||
| Flavodoxin_1 | 673..863 | CDD:278677 | 67/189 (35%) | ||
| Nitric_oxide_synthase | 931..1328 | CDD:99799 | 177/401 (44%) | ||
| Nos2 | NP_035057.1 | DINNN-motif, mediates interaction with SPSB1, SPSB2 and SPSB4. /evidence=ECO:0000269|PubMed:20603330 | 23..27 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 37..59 | ||||
| NOS_oxygenase_euk | 78..490 | CDD:238410 | 230/410 (56%) | ||
| Calmodulin-binding. /evidence=ECO:0000255 | 503..523 | 6/19 (32%) | |||
| CysJ | 534..1121 | CDD:223446 | 260/656 (40%) | ||
| Flavodoxin_1 | 535..666 | CDD:278677 | 67/189 (35%) | ||
| FNR_like | 730..1126 | CDD:297884 | 178/405 (44%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 526 | 1.000 | Domainoid score | I296 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG46820 | |
| OrthoDB | 1 | 1.010 | - | - | D56017at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001418 | |
| OrthoInspector | 1 | 1.000 | - | - | otm44105 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_103176 | |
| Panther | 1 | 1.100 | - | - | O | PTHR19384 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 9 | 8.930 | |||||