DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17134 and YPS5

DIOPT Version :9

Sequence 1:	NP_609458.1	Gene:	CG17134 / 34494	FlyBaseID:	FBgn0032304	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_011255.1	Gene:	YPS5 / 852632	SGDID:	S000003228	Length:	165	Species:	Saccharomyces cerevisiae

Alignment Length:	147	Identity:	35/147 - (23%)
Similarity:	58/147 - (39%)	Gaps:	28/147 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 SVKAEKTVLASKYS----FLAETSFSVSSSGA---------TENLHNSMNN---EYYGVIAIGTP 85
            |:....|||.|..|    |..:....:.:.|.         .|.|:.::.|   .|...:.||||
Yeast    12 SLMCSLTVLGSSASSYVKFPVQKFADIINIGTQDVSTVFKRNEVLNTTVINGIGVYVVKMEIGTP 76

  Fly    86 EQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASSTYVANGEEFAIEYGTGSLSGFLSN 150
            .|...:..||||:::.|        |.|...:.|..|..|.....:..|....: ||..|...|.
Yeast    77 PQTVYLQLDTGSSDMIV--------NNADIAYCKSMSDGSDYASTDNYELTATF-TGPRSTTTSP 132

  Fly   151 DIVTIA---GISIQNQT 164
            :::|::   |::...:|
Yeast   133 ELITLSALIGVNSMQET 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:299705	25/101 (25%)
CG17134	NP_609458.1	Asp	75..388	CDD:278455	24/93 (26%)
YPS5	NP_011255.1	pepsin_retropepsin_like	65..>100	CDD:416259	13/42 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900