DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17134 and YPS7

DIOPT Version :9

Sequence 1:	NP_609458.1	Gene:	CG17134 / 34494	FlyBaseID:	FBgn0032304	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_010636.1	Gene:	YPS7 / 851950	SGDID:	S000002757	Length:	596	Species:	Saccharomyces cerevisiae

Alignment Length:	449	Identity:	95/449 - (21%)
Similarity:	165/449 - (36%)	Gaps:	113/449 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TVLASKYSFLAET---SFSVSSSGAT----ENLHNSMNNEYYGVIAI--------------GTPE 86
            |.|...|.:|..|   .|:.:|:..|    ::..:|...|.:.|:|:              |||.
Yeast     2 TCLILWYLWLISTFQLEFATASTANTTTTAKSGTSSSTEEPFPVLAVGKDGRGNYYVNSTFGTPG 66

  Fly    87 QRFNILFDTGSANLWVPSASCPASNTACQRHNKYDS-----SASSTYVANGEEFAIEYGTG-SLS 145
            ||..:|.|.....:.:.|.:..:.|.....::|:.|     |.||..|:.|:.:.|.:..| :::
Yeast    67 QRQRLLVDIIQPYINLVSGTSESHNEYSGVYHKHPSYLMNDSTSSVPVSPGQIYEISFIDGRAVN 131

  Fly   146 GFLSNDIVTIAGISIQN----------------QTFGEALSEPGTTFVDA-----PFAGILGLAF 189
            ..|..|.:....:|.:|                |....:||....:|.|.     ..:|:|||:.
Yeast   132 CTLVTDDMNFTNVSSENSSTALITDLMVTRDNVQFNSGSLSISNVSFFDIQSSNFKTSGLLGLSG 196

  Fly   190 SAI----AVDGVTPPFDNMISQGLLDEPVI-------------SFYLKRQGTAVRGGELILGGID 237
            ...    |:|.......:.....|.|..:|             |.|...:......|:|:|||:|
Yeast   197 KVTNPGNAIDSSQYTEQSYFLSLLKDADIIESSSYSLWLAGDTSTYKTYRDPISNCGKLLLGGVD 261

  Fly   238 SSLYRGSL------TYV-PVS------VPAYWQFKVNTIKTNGTLLCNGCQ-----AIADTGTSL 284
            .||:.|:|      .|| |||      .|......:..:..:|..|....:     |:.|:.:|:
Yeast   262 PSLFTGTLGKFDLIPYVDPVSNAVSVGYPIVPLGPIYIVSNSGQSLNMTSKDFLSPALLDSTSSV 326

  Fly   285 IAVPLAAYRKINRQLGAT--DNDGEAFVRCGRVSSLPKVNLNIGGTVFTLAPRDYIVKVT----- 342
            ..:|.:...:|..|:.||  ::.....|:|    |:..:.:::|   |.|  |:..:::.
Yeast   327 SYLPTSTIIQIAVQIAATYVESLDRWLVQC----SIADMGVSLG---FRL--RELTIEIPLRDLL 382

  Fly   343 --------------QNGQTYCMSAFTYMEGLSFWILGDVFIGKFYTVFDKGNERIGFAR 387
                          .:||..|.............|||:.||...|...|..:..|..|:
Yeast   383 SSTYDTSTNSSMFFSSGQEACFLTLYANTNTGVNILGEAFIKNIYMAMDLEDNTIAIAQ 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:299705	86/412 (21%)
CG17134	NP_609458.1	Asp	75..388	CDD:278455	86/410 (21%)
YPS7	NP_010636.1	pepsin_retropepsin_like	162..442	CDD:416259	61/289 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4148
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850