Protein Alignment CG17134 and bace1

DIOPT Version :9

• Sequence 1: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_001072485.1
• Gene: bace1 / 779940
• XenbaseID: XB-GENE-5787150
• Length: 502
• Species: Xenopus tropicalis
• Alignment Length: 372
• Identity: 111/372 - (29%)
• Similarity: 172/372 - (46%)
• Gaps: 57/372 - (15%)

  Fly    66 ENLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASSTYVA 130
            :||.......||..:.:|||.|..|||.||||:|..|.:|..|    ..:|:  |....|.||..
 Frog    66 DNLRGKSGQGYYVEMRVGTPPQTLNILVDTGSSNFAVGAAPHP----FLKRY--YHRQHSRTYRD 124

  Fly   131 NGEEFAIEYGTGSLSGFLSNDIVTIA-GISIQNQTFGEALSEPGTTFVD-APFAGILGLAFSAIA 193
            ......:.|..|...|.|..|:|||. |.::.......|:::....|:: :.:.||||||::.||
 Frog   125 VRRGVYVPYTQGKWEGELGTDLVTIPHGPNVTVTANIAAITDSDKFFINGSNWEGILGLAYAEIA 189

  Fly   194 --VDGVTPPFDNMISQGLLDEPVISFYLKRQGT----------AVRGGELILGGIDSSLYRGSLT 246
              .|.:.|.||:::.|..:  |.| |.|:..||          |..||.:::||||.|||.||:.
 Frog   190 RPDDTLEPFFDSLVKQTRV--PNI-FSLQLCGTGFHFNESDTSASVGGSMVIGGIDPSLYIGSIW 251

  Fly   247 YVPVSVPAYWQFKVNTIKTNGTLLCNGC------QAIADTGTSLIAVPLAAYRKINRQLGATDND 305
            |.|:....|::..:..|:.||..|...|      ::|.|:||:.:.:|...:....:.:.|..:.
 Frog   252 YTPIRKEWYYEVIIVKIEINGQDLHMDCKEYNYDKSIVDSGTTNLRLPKRVFDAAVKSIKAASST 316

  Fly   306 ---------GEAFVRCGRVSS-----LPKVNLNIGGTV------FTLAPRDYI--VKVTQNGQTY 348
                     ||..| |.:..:     .|.::|.:.|.|      .|:.|:.|:  |:.....|..
 Frog   317 EKFPDGFWLGEQLV-CWQEGTTPWHIFPVISLYLMGEVANQSFKITILPQQYLRPVEDIATAQED 380

  Fly   349 CMSAFTYMEGLSFWILGDVFIGKFYTVFDKGNERIGFA----RVADY 391
            |.. |...:..:..::|.|.:..||.|||:.|:|||||    .|.||
 Frog   381 CYK-FAVSQSTTGTVMGAVIMEGFYVVFDRANKRIGFAVSTCHVHDY 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:299705	104/357 (29%)
		Asp	75..388	CDD:278455	106/358 (30%)
bace1	NP_001072485.1	beta_secretase_like	73..438	CDD:133140	109/365 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910