Protein Alignment CG17134 and ctsd

DIOPT Version :10

• Sequence 1: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_571785.2
• Gene: ctsd / 65225
• ZFINID: ZDB-GENE-010131-8
• Length: 398
• Species: Danio rerio
• Alignment Length: 396
• Identity: 171/396 - (43%)
• Similarity: 243/396 - (61%)
• Gaps: 14/396 - (3%)

  Fly     3 QLLVLLVLVGIGHSAAKLNRVQLQVNKNFTKT-HGSVKAEKTVLASKYSFLAETSFSVSSSGATE 66
            ::..||::|....::..:.|:.|:..:...:| ..|.::.:.:::|..|......|..|:....|
Zfish     2 RIAFLLLVVAFFCTSDAIVRIPLKKFRTLRRTLSDSGRSLEELVSSSNSLKYNLGFPASNDPTPE 66

  Fly    67 NLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASSTYVAN 131
            .|.|.::.:|||.|.:|||.|.|.::|||||:||||||..|..::.||..|:||:...|||||.|
Zfish    67 TLKNYLDAQYYGEIGLGTPVQTFTVVFDTGSSNLWVPSVHCSLTDIACLLHHKYNGGKSSTYVKN 131

  Fly   132 GEEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVDAPFAGILGLAFSAIAVDG 196
            |.:|||:||:|||||:||.|..||..|:::.|.||||:.:||..|:.|.|.||||:|:..|||||
Zfish   132 GTQFAIQYGSGSLSGYLSQDTCTIGDIAVEKQIFGEAIKQPGVAFIAAKFDGILGMAYPRIAVDG 196

  Fly   197 VTPPFDNMISQGLLDEPVISFYLKRQGTAVRGGELILGGIDSSLYRGSLTYVPVSVPAYWQFKVN 261
            |.|.||.|:||..:::.|.||||.|......||||:|||.|...|.|...||.:|..||||..::
Zfish   197 VPPVFDMMMSQKKVEKNVFSFYLNRNPDTQPGGELLLGGTDPKYYTGDFNYVDISRQAYWQIHMD 261

  Fly   262 TIKT-NGTLLC-NGCQAIADTGTSLIAVPLAAYRKINRQLGATD-NDGEAFVRCGRVSSLPKVNL 323
            .:.. :|..|| .||:||.|||||||..|.|..:.:.:.:||.. ..||..|.|.:|.:||.::.
Zfish   262 GMSIGSGLSLCKGGCEAIVDTGTSLITGPAAEVKALQKAIGAIPLMQGEYMVDCKKVPTLPTISF 326

  Fly   324 NIGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYMEGLS-------FWILGDVFIGKFYTVFDKGNE 381
            ::||.|::|....||:|.:|.|...|:|.|.   ||.       .|||||||||::|||||:.|.
Zfish   327 SLGGKVYSLTGEQYILKESQGGHDICLSGFM---GLDIPPPAGPLWILGDVFIGQYYTVFDRENN 388

  Fly   382 RIGFAR 387
            |:|||:
Zfish   389 RVGFAK 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:472175	156/325 (48%)
ctsd	NP_571785.2	A1_Propeptide	21..44	CDD:462326	4/22 (18%)
		Cathepsin_D2	70..394	CDD:133157	157/326 (48%)