Protein Alignment CG17134 and Pga5

DIOPT Version :9

• Sequence 1: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_067428.2
• Gene: Pga5 / 58803
• MGIID: 1915935
• Length: 387
• Species: Mus musculus
• Alignment Length: 398
• Identity: 148/398 - (37%)
• Similarity: 222/398 - (55%)
• Gaps: 31/398 - (7%)

  Fly     1 MRQLLVLLVLVGIGHSAAKLNRVQLQVNKNFTKTHGSVKAEKTVLASKYSFLAETSFSVSSSGAT 65
            :.:.||.:.|:.|  .:.:.|..:.||.|::.:.:...:|.  ||..:....|.|         .
Mouse    12 LSECLVKIPLMKI--KSMRENLRESQVLKDYLEKYPRSRAH--VLLEQRRNPAVT---------Y 63

  Fly    66 ENLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASSTYVA 130
            |.:.|.::..|.|:|:||||.|.|.::.||||:.|||||..|  |:.||..|..::...|||::.
Mouse    64 EPMRNYLDLVYIGIISIGTPPQEFRVVLDTGSSVLWVPSIYC--SSPACAHHKAFNPLRSSTFLV 126

  Fly   131 NGEEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVDAPFAGILGLAFSAIAVD 195
            :|....:.||:|.:||||:.|.|.|..:::..|.||.:|.|||.....|.|.|||||.:..:.:.
Mouse   127 SGRPVNVAYGSGEMSGFLAYDTVRIGDLTVVAQAFGLSLEEPGIFMEYAVFDGILGLGYPNLGLQ 191

  Fly   196 GVTPPFDNMISQGLLDEPVISFYLKRQGTAVRGGELILGGIDSSLYRGSLTYVPVSVPAYWQFKV 260
            |:||.|||:..|||:.:.:.:|||..:..  :|..|:|||:|.|.|.|.|.:||||.|:|||..|
Mouse   192 GITPVFDNLWLQGLIPQNLFAFYLSSKDE--KGSMLMLGGVDPSYYHGELHWVPVSKPSYWQLAV 254

  Fly   261 NTIKTNGTLL-CN-GCQAIADTGTSLIAVPLAAYRKINRQLGA-TDNDGEAFVRCGRVSSLPKVN 322
            ::|..||.:: |: |||.|.||||||:..|.::...|...:|| ...|||.|::|..:::||.:.
Mouse   255 DSISMNGEVIACDGGCQGIMDTGTSLLTGPRSSIVNIQNLIGAKASGDGEYFLKCDTINTLPDIV 319

  Fly   323 LNIGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYMEGL------SFWILGDVFIGKFYTVFDKGNE 381
            ..||...:.:....||.|...:.   |.|.|.  ||:      ..|:|||||:..::||||:.|.
Mouse   320 FTIGSVTYPVPASAYIRKDRSHN---CRSNFE--EGMDDPSDPEMWVLGDVFLRLYFTVFDRANN 379

  Fly   382 RIGFARVA 389
            |||.|..|
Mouse   380 RIGLAPAA 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:299705	132/324 (41%)
		Asp	75..388	CDD:278455	132/321 (41%)
Pga5	NP_067428.2	A1_Propeptide	16..44	CDD:285240	8/29 (28%)
		pepsin_retropepsin_like	64..385	CDD:299705	133/329 (40%)
		Asp	74..386	CDD:278455	132/320 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.860