Protein Alignment CG17134 and PGC

DIOPT Version :9

• Sequence 1: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_002621.1
• Gene: PGC / 5225
• HGNCID: 8890
• Length: 388
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 160/410 - (39%)
• Similarity: 229/410 - (55%)
• Gaps: 43/410 - (10%)

  Fly     1 MRQLLVLLVLVGIGHSAAKLNRVQLQVNKNFTKTHGSVKAEKTVL-----------ASKYSFLAE 54
            |:.::|:||.:.:..:|  :.:|.|:..|:..:|    ..||.:|           |.||.|
Human     1 MKWMVVVLVCLQLLEAA--VVKVPLKKFKSIRET----MKEKGLLGEFLRTHKYDPAWKYRF--- 56

  Fly    55 TSFSVSSSGATENLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNK 119
                 .....|......|:..|:|.|:||||.|.|.:||||||:||||||..|  .:.||..|::
Human    57 -----GDLSVTYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC--QSQACTSHSR 114

  Fly   120 YDSSASSTYVANGEEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVDAPFAGI 184
            ::.|.||||..||:.|:::||:|||:||...|.:|:..|.:.||.||.:.:||||.||.|.|.||
Human   115 FNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGI 179

  Fly   185 LGLAFSAIAVDGVTPPFDNMISQGLLDEPVISFYL-KRQGTAVRGGELILGGIDSSLYRGSLTYV 248
            :|||:.|::||..|.....|:.:|.|..||.|.|| .:||::  ||.::.||:|||||.|.:.:.
Human   180 MGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSS--GGAVVFGGVDSSLYTGQIYWA 242

  Fly   249 PVSVPAYWQFKVNTIKTNGTL--LCN-GCQAIADTGTSLIAVPLAAYRKINRQLGATDND-GEAF 309
            ||:...|||..:......|..  .|: |||||.||||||:.||......:.:..||.::: |:..
Human   243 PVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFL 307

  Fly   310 VRCGRVSSLPKVNLNIGGTVFTLAPRDYIVKVTQNGQTYCMSAF--TYM---EGLSFWILGDVFI 369
            |.|..:.:||.:...|.|..|.|.|..||  ::.||  ||....  ||:   .|...|||||||:
Human   308 VNCNSIQNLPSLTFIINGVEFPLPPSSYI--LSNNG--YCTVGVEPTYLSSQNGQPLWILGDVFL 368

  Fly   370 GKFYTVFDKGNERIGFARVA 389
            ..:|:|:|.||.|:|||..|
Human   369 RSYYSVYDLGNNRVGFATAA 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:299705	140/325 (43%)
		Asp	75..388	CDD:278455	141/322 (44%)
PGC	NP_002621.1	A1_Propeptide	18..46	CDD:285240	7/31 (23%)
		gastricsin	70..387	CDD:133144	141/324 (44%)
		Asp	72..387	CDD:278455	141/322 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151472
Domainoid	1	1.000	297	1.000	Domainoid score	I1463
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	319	1.000	Inparanoid score	I2536
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	1	1.000	-	-		mtm8487
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.810