DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17134 and pga4

DIOPT Version :9

Sequence 1:	NP_609458.1	Gene:	CG17134 / 34494	FlyBaseID:	FBgn0032304	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	XP_002942158.1	Gene:	pga4 / 496914	XenbaseID:	XB-GENE-979768	Length:	384	Species:	Xenopus tropicalis

Alignment Length:	404	Identity:	164/404 - (40%)
Similarity:	229/404 - (56%)	Gaps:	38/404 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QLLVLLVLVGIGHSAAKL---------NRVQ-LQVNKNFTKTHGSVKAEKTVLASKYSFLAETSF 57
            :||:||.||.:.....|:         ||:| |.:..::.|.:....      ||||       |
Frog     2 KLLLLLGLVVLSECVVKVPLRKGESFRNRLQRLGLLGDYLKKYPYNP------ASKY-------F 53

  Fly    58 SVSSSGATENLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDS 122
            ...:..:.|.|.|.|:.||||.|:||||.|.|.::||||||||||||..|  |::||..||:::.
Frog    54 PTLAQSSAEVLQNYMDIEYYGTISIGTPPQEFTVIFDTGSANLWVPSVYC--SSSACTNHNRFNP 116

  Fly   123 SASSTYVANGEEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVDAPFAGILGL 187
            ..|:|:.|.....:|:|||||:||||..|.:.:..|.|.||.||.:.||||:....:||.|||||
Frog   117 QQSTTFQATNTPVSIQYGTGSMSGFLGYDTLQVGNIKISNQMFGLSESEPGSFLYYSPFDGILGL 181

  Fly   188 AFSAIAVDGVTPPFDNMISQGLLDEPVISFYLKRQGTAVRGGELILGGIDSSLYRGSLTYVPVSV 252
            ||.:||....||.||||.||||:.:.:.|.||...|.:  |..::.||:|:|.|.|||.:||::.
Frog   182 AFPSIASSQATPVFDNMWSQGLIPQNLFSVYLSSDGQS--GSYVLFGGVDTSYYSGSLNWVPLTA 244

  Fly   253 PAYWQFKVNTIKTNGTLL-CN-GCQAIADTGTSLIAVPLAAYRKINRQLGAT-DNDGEAFVRCGR 314
            ..|||..:::|..||.:: |: .||||.||||||:..|......|...:||: |::|:..:.|..
Frog   245 ETYWQIILDSISINGQVIACSQSCQAIVDTGTSLMTGPTTPIANIQYYIGASQDSNGQYVINCNN 309

  Fly   315 VSSLPKVNLNIGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYM----EGLSFWILGDVFIGKFYTV 375
            :|::|.:...|.|..:.|.|..|   |.|| |..|.|.|..|    .....||||||||.:::.|
Frog   310 ISNMPTIVFTINGVQYPLPPTAY---VRQN-QQGCSSGFQAMTLPTNSGDLWILGDVFIRQYFVV 370

  Fly   376 FDKGNERIGFARVA 389
            ||:.|..:..|.||
Frog   371 FDRTNNYVAMAPVA 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:299705	142/322 (44%)
CG17134	NP_609458.1	Asp	75..388	CDD:278455	141/319 (44%)
pga4	XP_002942158.1	A1_Propeptide	16..44	CDD:369623	6/27 (22%)
pga4	XP_002942158.1	pepsin_A	62..382	CDD:133145	144/327 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.110