Protein Alignment CG17134 and Ren

DIOPT Version :10

• Sequence 1: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_036774.4
• Gene: Ren / 24715
• RGDID: 3554
• Length: 402
• Species: Rattus norvegicus
• Alignment Length: 346
• Identity: 153/346 - (44%)
• Similarity: 208/346 - (60%)
• Gaps: 17/346 - (4%)

  Fly    51 FLAETSFSVSSSGATENLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQ 115
            |:.::||:..:|...  |.|.::.:|||.|.||||.|.|.::||||||||||||..|....|||:
  Rat    61 FIKKSSFTNVTSPVV--LTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACE 123

  Fly   116 RHNKYDSSASSTYVANGEEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVDAP 180
            .||.||||.||:|:.||.||.|.||:|.:.||||.|:||:.|| |..|||||....|...|:.|.
  Rat   124 IHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGI-IVTQTFGEVTELPLIPFMLAK 187

  Fly   181 FAGILGLAFSAIAVDGVTPPFDNMISQGLLDEPVISFYLKRQGTAVRGGELILGGIDSSLYRGSL 245
            |.|:||:.|.|.|||||.|.||:::||.:|.|.|.|.|..|: :.:.|||::|||.|...|:|:.
  Rat   188 FDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRE-SHLLGGEVVLGGSDPQHYQGNF 251

  Fly   246 TYVPVSVPAYWQFKVNTIKTN-GTLLC-NGCQAIADTGTSLIAVPLAAYRKINRQLGATDNDGEA 308
            .||.:|....||..:..:... .|||| .||.|:.|||||.|:.|.::.:.|.:.||..:.....
  Rat   252 HYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKRANN 316

  Fly   309 F-VRCGRVSSLPKVNLNIGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYMEGLSF-------WILG 365
            : |.|.:|.:||.::..:||..:||:..||:.|........|:.|   ::||..       |:||
  Rat   317 YVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCILA---LQGLDIPPPTGPVWVLG 378

  Fly   366 DVFIGKFYTVFDKGNERIGFA 386
            ..||.||||.||:.|.|||||
  Rat   379 ATFIRKFYTEFDRHNNRIGFA 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:472175	146/325 (45%)
Ren	NP_036774.4	A1_Propeptide	31..64	CDD:462326	1/2 (50%)
		renin_like	76..401	CDD:133154	149/329 (45%)