Sequence 1: | NP_609458.1 | Gene: | CG17134 / 34494 | FlyBaseID: | FBgn0032304 | Length: | 391 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_036236.1 | Gene: | BACE1 / 23621 | HGNCID: | 933 | Length: | 501 | Species: | Homo sapiens |
Alignment Length: | 361 | Identity: | 105/361 - (29%) |
---|---|---|---|
Similarity: | 166/361 - (45%) | Gaps: | 49/361 - (13%) |
- Green bases have known domain annotations that are detailed below.
Fly 66 ENLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASSTYVA 130
Fly 131 NGEEFAIEYGTGSLSGFLSNDIVTIA-GISIQNQTFGEALSEPGTTFVD-APFAGILGLAFSAIA 193
Fly 194 --VDGVTPPFDNMISQGLLDEPVISFYLKRQG--------TAVRGGELILGGIDSSLYRGSLTYV 248
Fly 249 PVSVPAYWQFKVNTIKTNGTLLCNGC------QAIADTGTSLIAVPLAAYRKINRQLGATDND-- 305
Fly 306 -------GEAFVRCGRVSS-----LPKVNLNIGGTV------FTLAPRDYI--VKVTQNGQTYCM 350
Fly 351 SAFTYMEGLSFWILGDVFIGKFYTVFDKGNERIGFA 386 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
CG17134 | NP_609458.1 | pepsin_retropepsin_like | 70..386 | CDD:299705 | 101/355 (28%) |
Asp | 75..388 | CDD:278455 | 103/352 (29%) | ||
BACE1 | NP_036236.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 39..58 | ||
beta_secretase_like | 72..437 | CDD:133140 | 103/354 (29%) | ||
Interaction with RTN3 | 479..501 | ||||
DXXLL. /evidence=ECO:0000269|PubMed:15886016 | 496..500 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165151464 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG1339 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.740 |