Protein Alignment CG17134 and Ren2

DIOPT Version :10

• Sequence 1: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_112470.2
• Gene: Ren2 / 19702
• MGIID: 97899
• Length: 424
• Species: Mus musculus
• Alignment Length: 327
• Identity: 147/327 - (44%)
• Similarity: 200/327 - (61%)
• Gaps: 11/327 - (3%)

  Fly    68 LHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASSTYVANG 132
            |.|.:|::|||.|.||||.|.|.::||||||||||||..|.....||..|:.|:||.||:|:.||
Mouse    98 LTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENG 162

  Fly   133 EEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVDAPFAGILGLAFSAIAVDGV 197
            ::|.|.||:|.:.||||.|.||:.||:: .|||||....|...|:.|.|.|:||:.|.|.||.||
Mouse   163 DDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAQFDGVLGMGFPAQAVGGV 226

  Fly   198 TPPFDNMISQGLLDEPVISFYLKRQGTAVRGGELILGGIDSSLYRGSLTYVPVSVPAYWQFKVNT 262
            ||.||:::|||:|.|.|.|.|..| |..:.|||::|||.|...|:|...||.:|....||..:..
Mouse   227 TPVFDHILSQGVLKEKVFSVYYNR-GPHLLGGEVVLGGSDPEHYQGDFHYVSLSKTDSWQITMKG 290

  Fly   263 IKT-NGTLLC-NGCQAIADTGTSLIAVPLAAYRKINRQLGATDND-GEAFVRCGRVSSLPKVNLN 324
            :.. :.|||| .||:.:.|||:|.|:.|.::.:.|.:.|||.:.. .|..|.|.:|.:||.::.|
Mouse   291 VSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIMQALGAKEKRLHEYVVSCSQVPTLPDISFN 355

  Fly   325 IGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYME-----GLSFWILGDVFIGKFYTVFDKGNERIG 384
            :||..:||:..||:::........|..|...|:     | ..|:||..||.||||.||:.|.|||
Mouse   356 LGGRAYTLSSTDYVLQYPNRRDKLCTVALHAMDIPPPTG-PVWVLGATFIRKFYTEFDRHNNRIG 419

  Fly   385 FA 386
            ||
Mouse   420 FA 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:472175	144/323 (45%)
Ren2	NP_112470.2	A1_Propeptide	53..>71	CDD:462326
		renin_like	98..423	CDD:133154	147/327 (45%)